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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 1
2004 2
2005 5
2006 5
2007 3
2008 5
2009 7
2010 4
2011 4
2012 5
2013 5
2014 11
2015 10
2016 12
2017 10
2018 16
2019 8
2020 11
2021 8
2022 3
2023 5
2024 3

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127 results

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Page 1
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2).
Day JEH, Berdini V, Castro J, Chessari G, Davies TG, Day PJ, St Denis JD, Fujiwara H, Fukaya S, Hamlett CCF, Hearn K, Hiscock SD, Holvey RS, Ito S, Kandola N, Kodama Y, Liebeschuetz JW, Martins V, Matsuo K, Mortenson PN, Muench S, Nakatsuru Y, Ochiiwa H, Palmer N, Peakman T, Price A, Reader M, Rees DC, Rich SJ, Shah A, Shibata Y, Smyth T, Twigg DG, Wallis NG, Williams G, Wilsher NE, Woodhead A, Shimamura T, Johnson CN. Day JEH, et al. Among authors: johnson cn. J Med Chem. 2024 Mar 28;67(6):4655-4675. doi: 10.1021/acs.jmedchem.3c02118. Epub 2024 Mar 10. J Med Chem. 2024. PMID: 38462716
Prognostic Value of Multiplexed Assays of Variant Effect and Automated Patch-clamping for KCNH2-LQTS Risk Stratification.
O'Neill MJ, Ng CA, Aizawa T, Sala L, Bains S, Denjoy I, Winbo A, Ullah R, Shen Q, Tan CY, Kozek K, Vanags LR, Mitchell DW, Shen A, Wada Y, Kashiwa A, Crotti L, Dagradi F, Musu G, Spazzolini C, Neves R, Bos JM, Giudicessi JR, Bledsoe X, Lancaster M, Glazer AM, Roden DM, Leenhardt A, Salem JE, Earle N, Stiles R, Agee T, Johnson CN, Horie M, Skinner J, Extramiana F, Ackerman MJ, Schwartz PJ, Ohno S, Vandenberg JI, Kroncke BM. O'Neill MJ, et al. Among authors: johnson cn. medRxiv [Preprint]. 2024 Feb 5:2024.02.01.24301443. doi: 10.1101/2024.02.01.24301443. medRxiv. 2024. PMID: 38370760 Free PMC article. Preprint.
KBTBD13 is an actin-binding protein that modulates muscle kinetics.
de Winter JM, Molenaar JP, Yuen M, van der Pijl R, Shen S, Conijn S, van de Locht M, Willigenburg M, Bogaards SJ, van Kleef ES, Lassche S, Persson M, Rassier DE, Sztal TE, Ruparelia AA, Oorschot V, Ramm G, Hall TE, Xiong Z, Johnson CN, Li F, Kiss B, Lozano-Vidal N, Boon RA, Marabita M, Nogara L, Blaauw B, Rodenburg RJ, Küsters B, Doorduin J, Beggs AH, Granzier H, Campbell K, Ma W, Irving T, Malfatti E, Romero NB, Bryson-Richardson RJ, van Engelen BG, Voermans NC, Ottenheijm CA. de Winter JM, et al. Among authors: johnson cn. J Clin Invest. 2024 Feb 1;134(3):e179111. doi: 10.1172/JCI179111. J Clin Invest. 2024. PMID: 38299595 Free PMC article. No abstract available.
Accelerated Chemical Reaction Optimization Using Multi-Task Learning.
Taylor CJ, Felton KC, Wigh D, Jeraal MI, Grainger R, Chessari G, Johnson CN, Lapkin AA. Taylor CJ, et al. Among authors: johnson cn. ACS Cent Sci. 2023 Apr 13;9(5):957-968. doi: 10.1021/acscentsci.3c00050. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252348 Free PMC article.
Human disease-associated calmodulin mutations alter calcineurin function through multiple mechanisms.
Williams RB, Alam Afsar MN, Tikunova S, Kou Y, Fang X, Somarathne RP, Gyawu RF, Knotts GM, Agee TA, Garcia SA, Losordo LD, Fitzkee NC, Kekenes-Huskey PM, Davis JP, Johnson CN. Williams RB, et al. Among authors: johnson cn. Cell Calcium. 2023 Jul;113:102752. doi: 10.1016/j.ceca.2023.102752. Epub 2023 May 10. Cell Calcium. 2023. PMID: 37245392 Free article.
A Brief Introduction to Chemical Reaction Optimization.
Taylor CJ, Pomberger A, Felton KC, Grainger R, Barecka M, Chamberlain TW, Bourne RA, Johnson CN, Lapkin AA. Taylor CJ, et al. Among authors: johnson cn. Chem Rev. 2023 Mar 22;123(6):3089-3126. doi: 10.1021/acs.chemrev.2c00798. Epub 2023 Feb 23. Chem Rev. 2023. PMID: 36820880 Free PMC article. Review.
127 results