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BQ788 reveals glial ETB receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus.
Mazzotta E, Grants I, Villalobos-Hernandez E, Chaudhuri S, McClain JL, Seguella L, Kendig DM, Blakeney BA, Murthy SK, Schneider R, Leven P, Wehner S, Harzman A, Grider JR, Gulbransen BD, Christofi FL. Mazzotta E, et al. Among authors: christofi fl. Br J Pharmacol. 2023 Oct;180(19):2550-2576. doi: 10.1111/bph.16145. Epub 2023 Jun 25. Br J Pharmacol. 2023. PMID: 37198101
Histamine-dependent interactions between mast cells, glia, and neurons are altered following early-life adversity in mice and humans.
McClain JL, Mazzotta EA, Maradiaga N, Duque-Wilckens N, Grants I, Robison AJ, Christofi FL, Moeser AJ, Gulbransen BD. McClain JL, et al. Among authors: christofi fl. Am J Physiol Gastrointest Liver Physiol. 2020 Dec 1;319(6):G655-G668. doi: 10.1152/ajpgi.00041.2020. Epub 2020 Sep 30. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32996781 Free PMC article.
Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction: Pathogenic Mechanisms and Novel Treatment Strategies Beyond Colorectal Enhanced Recovery After Surgery Protocols.
Mazzotta E, Villalobos-Hernandez EC, Fiorda-Diaz J, Harzman A, Christofi FL. Mazzotta E, et al. Among authors: christofi fl. Front Pharmacol. 2020 Nov 24;11:583422. doi: 10.3389/fphar.2020.583422. eCollection 2020. Front Pharmacol. 2020. PMID: 33390950 Free PMC article. Review.
Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders.
Liñán-Rico A, Turco F, Ochoa-Cortes F, Harzman A, Needleman BJ, Arsenescu R, Abdel-Rasoul M, Fadda P, Grants I, Whitaker E, Cuomo R, Christofi FL. Liñán-Rico A, et al. Among authors: christofi fl. Inflamm Bowel Dis. 2016 Aug;22(8):1812-34. doi: 10.1097/MIB.0000000000000854. Inflamm Bowel Dis. 2016. PMID: 27416040 Free PMC article.
Neuropharmacology of purinergic receptors in human submucous plexus: Involvement of P2X₁, P2X₂, P2X₃ channels, P2Y and A₃ metabotropic receptors in neurotransmission.
Liñán-Rico A, Wunderlich JE, Enneking JT, Tso DR, Grants I, Williams KC, Otey A, Michel K, Schemann M, Needleman B, Harzman A, Christofi FL. Liñán-Rico A, et al. Among authors: christofi fl. Neuropharmacology. 2015 Aug;95:83-99. doi: 10.1016/j.neuropharm.2015.02.014. Epub 2015 Feb 24. Neuropharmacology. 2015. PMID: 25724083 Free PMC article.
Purinergic autocrine regulation of mechanosensitivity and serotonin release in a human EC model: ATP-gated P2X3 channels in EC are downregulated in ulcerative colitis.
Liñán-Rico A, Wunderlich JE, Grants IS, Frankel WL, Xue J, Williams KC, Harzman AE, Enneking JT, Cooke HJ, Christofi FL. Liñán-Rico A, et al. Among authors: christofi fl. Inflamm Bowel Dis. 2013 Oct;19(11):2366-79. doi: 10.1097/MIB.0b013e31829ecf4d. Inflamm Bowel Dis. 2013. PMID: 23917247 Free PMC article.
71 results