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On the Evolution of the Cardiac Pacemaker.
Burkhard S, van Eif V, Garric L, Christoffels VM, Bakkers J. Burkhard S, et al. Among authors: christoffels vm. J Cardiovasc Dev Dis. 2017 Apr 27;4(2):4. doi: 10.3390/jcdd4020004. J Cardiovasc Dev Dis. 2017. PMID: 29367536 Free PMC article. Review.
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.
Hoogaars WM, Engel A, Brons JF, Verkerk AO, de Lange FJ, Wong LY, Bakker ML, Clout DE, Wakker V, Barnett P, Ravesloot JH, Moorman AF, Verheijck EE, Christoffels VM. Hoogaars WM, et al. Among authors: christoffels vm. Genes Dev. 2007 May 1;21(9):1098-112. doi: 10.1101/gad.416007. Genes Dev. 2007. PMID: 17473172 Free PMC article.
Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43.
Boogerd CJ, Wong LY, van den Boogaard M, Bakker ML, Tessadori F, Bakkers J, 't Hoen PA, Moorman AF, Christoffels VM, Barnett P. Boogerd CJ, et al. Among authors: christoffels vm. Cell Mol Life Sci. 2011 Dec;68(23):3949-61. doi: 10.1007/s00018-011-0693-7. Epub 2011 May 3. Cell Mol Life Sci. 2011. PMID: 21538160 Free PMC article.
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells.
Bakker ML, Boink GJ, Boukens BJ, Verkerk AO, van den Boogaard M, den Haan AD, Hoogaars WM, Buermans HP, de Bakker JM, Seppen J, Tan HL, Moorman AF, 't Hoen PA, Christoffels VM. Bakker ML, et al. Among authors: christoffels vm. Cardiovasc Res. 2012 Jun 1;94(3):439-49. doi: 10.1093/cvr/cvs120. Epub 2012 Mar 14. Cardiovasc Res. 2012. PMID: 22419669
Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
van den Boogaard M, Wong LY, Tessadori F, Bakker ML, Dreizehnter LK, Wakker V, Bezzina CR, 't Hoen PA, Bakkers J, Barnett P, Christoffels VM. van den Boogaard M, et al. Among authors: christoffels vm. J Clin Invest. 2012 Jul;122(7):2519-30. doi: 10.1172/JCI62613. Epub 2012 Jun 18. J Clin Invest. 2012. PMID: 22706305 Free PMC article.
The formation and function of the cardiac conduction system.
van Weerd JH, Christoffels VM. van Weerd JH, et al. Among authors: christoffels vm. Development. 2016 Jan 15;143(2):197-210. doi: 10.1242/dev.124883. Development. 2016. PMID: 26786210 Free article. Review.
230 results