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Structure-Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR.
Carlino L, Christodoulou MS, Restelli V, Caporuscio F, Foschi F, Semrau MS, Costanzi E, Tinivella A, Pinzi L, Lo Presti L, Battistutta R, Storici P, Broggini M, Passarella D, Rastelli G. Carlino L, et al. Among authors: christodoulou ms. ChemMedChem. 2018 Dec 20;13(24):2627-2634. doi: 10.1002/cmdc.201800687. Epub 2018 Nov 20. ChemMedChem. 2018. PMID: 30457710 Free article.
'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells.
Colombo F, Tintori C, Furlan A, Borrelli S, Christodoulou MS, Dono R, Maina F, Botta M, Amat M, Bosch J, Passarella D. Colombo F, et al. Among authors: christodoulou ms. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4693-6. doi: 10.1016/j.bmcl.2012.05.078. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22738633
Camptothecin-7-yl-methanthiole: semisynthesis and biological evaluation.
Christodoulou MS, Zunino F, Zuco V, Borrelli S, Comi D, Fontana G, Martinelli M, Lorens JB, Evensen L, Sironi M, Pieraccini S, Dalla Via L, Gia OM, Passarella D. Christodoulou MS, et al. ChemMedChem. 2012 Dec;7(12):2134-43. doi: 10.1002/cmdc.201200322. Epub 2012 Oct 19. ChemMedChem. 2012. PMID: 23086693
Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins.
Christodoulou MS, Sacchetti A, Ronchetti V, Caufin S, Silvani A, Lesma G, Fontana G, Minicone F, Riva B, Ventura M, Lahtela-Kakkonen M, Jarho E, Zuco V, Zunino F, Martinet N, Dapiaggi F, Pieraccini S, Sironi M, Dalla Via L, Gia OM, Passarella D. Christodoulou MS, et al. Bioorg Med Chem. 2013 Nov 15;21(22):6920-8. doi: 10.1016/j.bmc.2013.09.030. Epub 2013 Sep 19. Bioorg Med Chem. 2013. PMID: 24103429
Chemical approaches to targeting drug resistance in cancer stem cells.
Sotiropoulou PA, Christodoulou MS, Silvani A, Herold-Mende C, Passarella D. Sotiropoulou PA, et al. Among authors: christodoulou ms. Drug Discov Today. 2014 Oct;19(10):1547-62. doi: 10.1016/j.drudis.2014.05.002. Epub 2014 May 10. Drug Discov Today. 2014. PMID: 24819719 Review.
Probing the binding site of abl tyrosine kinase using in situ click chemistry.
Peruzzotti C, Borrelli S, Ventura M, Pantano R, Fumagalli G, Christodoulou MS, Monticelli D, Luzzani M, Fallacara AL, Tintori C, Botta M, Passarella D. Peruzzotti C, et al. Among authors: christodoulou ms. ACS Med Chem Lett. 2013 Jan 15;4(2):274-7. doi: 10.1021/ml300394w. eCollection 2013 Feb 14. ACS Med Chem Lett. 2013. PMID: 24900659 Free PMC article.
Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.
Christodoulou MS, Calogero F, Baumann M, García-Argáez AN, Pieraccini S, Sironi M, Dapiaggi F, Bucci R, Broggini G, Gazzola S, Liekens S, Silvani A, Lahtela-Kakkonen M, Martinet N, Nonell-Canals A, Santamaría-Navarro E, Baxendale IR, Dalla Via L, Passarella D. Christodoulou MS, et al. Eur J Med Chem. 2015 Mar 6;92:766-75. doi: 10.1016/j.ejmech.2015.01.038. Epub 2015 Jan 20. Eur J Med Chem. 2015. PMID: 25626146
59 results