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Leishmania LiHyC protein is immunogenic and induces protection against visceral leishmaniasis.
Machado AS, Lage DP, Vale DL, Freitas CS, Linhares FP, Cardoso JMO, Oliveira-da-Silva JA, Pereira IAG, Ramos FF, Tavares GSV, Ludolf F, Bandeira RS, Maia LGN, Menezes-Souza D, Duarte MC, Chávez-Fumagalli MA, Roatt BM, Christodoulides M, Martins VT, Coelho EAF. Machado AS, et al. Among authors: christodoulides m. Parasite Immunol. 2022 Aug;44(8):e12921. doi: 10.1111/pim.12921. Epub 2022 Apr 27. Parasite Immunol. 2022. PMID: 35437797
Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis.
Lage DP, Ribeiro PAF, Dias DS, Mendonça DVC, Ramos FF, Carvalho LM, Steiner BT, Tavares GSV, Martins VT, Machado AS, Oliveira-da-Silva JA, Santos TTO, Freitas CS, Oliveira JS, Roatt BM, Machado-de-Ávila RA, Humbert MV, Christodoulides M, Coelho EAF. Lage DP, et al. Among authors: christodoulides m. Vaccines (Basel). 2020 Jun 9;8(2):289. doi: 10.3390/vaccines8020289. Vaccines (Basel). 2020. PMID: 32526867 Free PMC article.
A candidate vaccine for human visceral leishmaniasis based on a specific T cell epitope-containing chimeric protein protects mice against Leishmania infantum infection.
Lage DP, Ribeiro PAF, Dias DS, Mendonça DVC, Ramos FF, Carvalho LM, de Oliveira D, Steiner BT, Martins VT, Perin L, Machado AS, Santos TTO, Tavares GSV, Oliveira-da-Silva JA, Oliveira JS, Roatt BM, Machado-de-Ávila RA, Teixeira AL, Humbert MV, Coelho EAF, Christodoulides M. Lage DP, et al. Among authors: christodoulides m. NPJ Vaccines. 2020 Aug 13;5:75. doi: 10.1038/s41541-020-00224-0. eCollection 2020. NPJ Vaccines. 2020. PMID: 32821440 Free PMC article.
Potential of recombinant LiHyQ, a novel Leishmania infantum protein, for the diagnosis of canine visceral leishmaniasis and as a diagnostic and prognostic marker for human leishmaniasis and human immunodeficiency virus co-infection: A preliminary study.
Santos TTO, Ramos FF, Gonçalves IAP, Tavares GSV, Ludolf F, Bandeira RS, Silva AM, Oliveira-da-Silva JA, Reis TAR, Machado AS, Lage DP, Freitas CS, Vale DL, Martins VT, Alves LA, Guimarães NS, Chaves AT, Chávez-Fumagalli MA, Cota GF, Silveira JAG, Tupinambás U, Gonçalves DU, Christodoulides M, Coelho EAF. Santos TTO, et al. Among authors: christodoulides m. Acta Trop. 2021 Dec;224:106126. doi: 10.1016/j.actatropica.2021.106126. Epub 2021 Sep 16. Acta Trop. 2021. PMID: 34537185
ChimLeish, a new recombinant chimeric protein evaluated as a diagnostic and prognostic marker for visceral leishmaniasis and human immunodeficiency virus coinfection.
Galvani NC, Machado AS, Lage DP, Freitas CS, Vale DL, de Oliveira D, Ludolf F, Ramos FF, Fernandes BB, Luiz GP, Mendonça DVC, Oliveira-da-Silva JA, Reis TAR, Tavares GSV, Chaves AT, Guimarães NS, Tupinambás U, Cota GF, Humbert MV, Martins VT, Christodoulides M, Coelho EAF, Machado-de-Ávila RA. Galvani NC, et al. Among authors: christodoulides m. Parasitol Res. 2021 Dec;120(12):4037-4047. doi: 10.1007/s00436-021-07342-1. Epub 2021 Oct 19. Parasitol Res. 2021. PMID: 34664113 Free PMC article.
Sensitive and specific serodiagnosis of tegumentary leishmaniasis using a new chimeric protein based on specific B-cell epitopes of Leishmania antigenic proteins.
Galvani NC, Machado AS, Lage DP, Martins VT, de Oliveira D, Freitas CS, Vale DL, Fernandes BB, Oliveira-da-Silva JA, Reis TAR, Santos TTO, Ramos FF, Bandeira RS, Ludolf F, Tavares GSV, Guimarães NS, Tupinambás U, Chávez-Fumagalli MA, Humbert MV, Gonçalves DU, Christodoulides M, Machado-de-Ávila RA, Coelho EAF. Galvani NC, et al. Among authors: christodoulides m. Microb Pathog. 2022 Jan;162:105341. doi: 10.1016/j.micpath.2021.105341. Epub 2021 Dec 6. Microb Pathog. 2022. PMID: 34883228
A recombinant Leishmania amastigote-specific protein, rLiHyG, with adjuvants, protects against infection with Leishmania infantum.
Machado AS, Lage DP, Vale DL, Freitas CS, Linhares FP, Cardoso JMO, Pereira IAG, Ramos FF, Tavares GSV, Ludolf F, Oliveira-da-Silva JA, Bandeira RS, Simões AC, Duarte MC, Oliveira JS, Christodoulides M, Chávez-Fumagalli MA, Roatt BM, Martins VT, Coelho EAF. Machado AS, et al. Among authors: christodoulides m. Acta Trop. 2022 Jun;230:106412. doi: 10.1016/j.actatropica.2022.106412. Epub 2022 Mar 16. Acta Trop. 2022. PMID: 35305943
130 results