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Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte-neuron lactate and ketone body shuttle systems.
Thevenet J, De Marchi U, Domingo JS, Christinat N, Bultot L, Lefebvre G, Sakamoto K, Descombes P, Masoodi M, Wiederkehr A. Thevenet J, et al. Among authors: christinat n. FASEB J. 2016 May;30(5):1913-26. doi: 10.1096/fj.201500182. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839375
MCFAs may have brain health benefits through the modulation of astrocyte metabolism leading to activation of shuttle systems that provide fuel to neighboring neurons in the form of lactate and ketone bodies.-Thevenet, J., De Marchi, U., Santo Domingo, J., Christinat, N
MCFAs may have brain health benefits through the modulation of astrocyte metabolism leading to activation of shuttle systems that provide fu …
Modulation of cerebral ketone metabolism following traumatic brain injury in humans.
Bernini A, Masoodi M, Solari D, Miroz JP, Carteron L, Christinat N, Morelli P, Beaumont M, Abed-Maillard S, Hartweg M, Foltzer F, Eckert P, Cuenoud B, Oddo M. Bernini A, et al. Among authors: christinat n. J Cereb Blood Flow Metab. 2020 Jan;40(1):177-186. doi: 10.1177/0271678X18808947. Epub 2018 Oct 24. J Cereb Blood Flow Metab. 2020. PMID: 30353770 Free PMC article.
23 results