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Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement.
Edeling MA, Austin SK, Shrestha B, Dowd KA, Mukherjee S, Nelson CA, Johnson S, Mabila MN, Christian EA, Rucker J, Pierson TC, Diamond MS, Fremont DH. Edeling MA, et al. Among authors: christian ea. PLoS Pathog. 2014 Apr 17;10(4):e1004072. doi: 10.1371/journal.ppat.1004072. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24743696 Free PMC article.
Atomic-level functional model of dengue virus Envelope protein infectivity.
Christian EA, Kahle KM, Mattia K, Puffer BA, Pfaff JM, Miller A, Paes C, Davidson E, Doranz BJ. Christian EA, et al. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18662-7. doi: 10.1073/pnas.1310962110. Epub 2013 Oct 24. Proc Natl Acad Sci U S A. 2013. PMID: 24158478 Free PMC article.
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