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Page 1
Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke.
Ma H, Campbell BCV, Parsons MW, Churilov L, Levi CR, Hsu C, Kleinig TJ, Wijeratne T, Curtze S, Dewey HM, Miteff F, Tsai CH, Lee JT, Phan TG, Mahant N, Sun MC, Krause M, Sturm J, Grimley R, Chen CH, Hu CJ, Wong AA, Field D, Sun Y, Barber PA, Sabet A, Jannes J, Jeng JS, Clissold B, Markus R, Lin CH, Lien LM, Bladin CF, Christensen S, Yassi N, Sharma G, Bivard A, Desmond PM, Yan B, Mitchell PJ, Thijs V, Carey L, Meretoja A, Davis SM, Donnan GA; EXTEND Investigators. Ma H, et al. Among authors: christensen s. N Engl J Med. 2019 May 9;380(19):1795-1803. doi: 10.1056/NEJMoa1813046. N Engl J Med. 2019. PMID: 31067369 Clinical Trial.
Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial.
Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, Barber PA, Bladin C, De Silva DA, Byrnes G, Chalk JB, Fink JN, Kimber TE, Schultz D, Hand PJ, Frayne J, Hankey G, Muir K, Gerraty R, Tress BM, Desmond PM; EPITHET investigators. Davis SM, et al. Lancet Neurol. 2008 Apr;7(4):299-309. doi: 10.1016/S1474-4422(08)70044-9. Epub 2008 Feb 28. Lancet Neurol. 2008. PMID: 18296121 Clinical Trial.
Postthrombolysis blood pressure elevation is associated with hemorrhagic transformation.
Butcher K, Christensen S, Parsons M, De Silva DA, Ebinger M, Levi C, Jeerakathil T, Campbell BC, Barber PA, Bladin C, Fink J, Tress B, Donnan GA, Davis SM; EPITHET Investigators. Butcher K, et al. Among authors: christensen s. Stroke. 2010 Jan;41(1):72-7. doi: 10.1161/STROKEAHA.109.563767. Epub 2009 Nov 19. Stroke. 2010. PMID: 19926841 Clinical Trial.
Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke.
Campbell BC, Christensen S, Butcher KS, Gordon I, Parsons MW, Desmond PM, Barber PA, Levi CR, Bladin CF, De Silva DA, Donnan GA, Davis SM; EPITHET Investigators. Campbell BC, et al. Among authors: christensen s. Stroke. 2010 Jan;41(1):82-8. doi: 10.1161/STROKEAHA.109.562116. Epub 2009 Dec 3. Stroke. 2010. PMID: 19959537 Clinical Trial.
The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET).
De Silva DA, Brekenfeld C, Ebinger M, Christensen S, Barber PA, Butcher KS, Levi CR, Parsons MW, Bladin CF, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. De Silva DA, et al. Among authors: christensen s. Stroke. 2010 Feb;41(2):295-9. doi: 10.1161/STROKEAHA.109.562827. Epub 2010 Jan 7. Stroke. 2010. PMID: 20056931 Clinical Trial.
Pretreatment diffusion- and perfusion-MR lesion volumes have a crucial influence on clinical response to stroke thrombolysis.
Parsons MW, Christensen S, McElduff P, Levi CR, Butcher KS, De Silva DA, Ebinger M, Barber PA, Bladin C, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. Parsons MW, et al. Among authors: christensen s. J Cereb Blood Flow Metab. 2010 Jun;30(6):1214-25. doi: 10.1038/jcbfm.2010.3. Epub 2010 Jan 20. J Cereb Blood Flow Metab. 2010. PMID: 20087363 Free PMC article. Clinical Trial.
Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials.
Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, Tilley BC, Davis SM, Donnan GA, Hacke W; ECASS, ATLANTIS, NINDS and EPITHET rt-PA Study Group; Allen K, Mau J, Meier D, del Zoppo G, De Silva DA, Butcher KS, Parsons MW, Barber PA, Levi C, Bladin C, Byrnes G. Lees KR, et al. Lancet. 2010 May 15;375(9727):1695-703. doi: 10.1016/S0140-6736(10)60491-6. Lancet. 2010. PMID: 20472172
1,997 results