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GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, Monson ET, Rentería ME, Walss-Bass C, Andreassen OA, Behera C, Bulik CM, Edenberg HJ, Kessler RC, Mann JJ, Nurnberger JI Jr, Pistis G, Streit F, Ursano RJ, Polimanti R, Dennis M, Garrett M, Hair L, Harvey P, Hauser ER, Hauser MA, Huffman J, Jacobson D, Madduri R, McMahon B, Oslin DW, Trafton J, Awasthi S, Berrettini WH, Bohus M, Chang X, Chen HC, Chen WJ, Christensen ED, Crow S, Duriez P, Edwards AC, Fernández-Aranda F, Galfalvy H, Gandal M, Gorwood P, Guo Y, Hafferty JD, Hakonarson H, Halmi KA, Hishimoto A, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Kim M, Klump KL, Levey DF, Li D, Liao SC, Lieb K, Lilenfeld L, Marshall CR, Mitchell JE, Okazaki S, Otsuka I, Pinto D, Powers A, Ramoz N, Ripke S, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Starnawska A, Strober M, Su MH, Thornton LM, Treasure J, Ware EB, Watson HJ, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Alda M, Alfredsson L, Appadurai V, Artigas MS, Van der Auwera S, Azevedo … See abstract for full author list ➔ Docherty AR, et al. Among authors: christensen ed. Am J Psychiatry. 2023 Oct 1;180(10):723-738. doi: 10.1176/appi.ajp.21121266. Am J Psychiatry. 2023. PMID: 37777856 Free PMC article.
Genome-wide significant regions in 43 Utah high-risk families implicate multiple genes involved in risk for completed suicide.
Coon H, Darlington TM, DiBlasi E, Callor WB, Ferris E, Fraser A, Yu Z, William N, Das SC, Crowell SE, Chen D, Anderson JS, Klein M, Jerominski L, Cannon D, Shabalin A, Docherty A, Williams M, Smith KR, Keeshin B, Bakian AV, Christensen E, Li QS, Camp NJ, Gray D. Coon H, et al. Mol Psychiatry. 2020 Nov;25(11):3077-3090. doi: 10.1038/s41380-018-0282-3. Epub 2018 Oct 23. Mol Psychiatry. 2020. PMID: 30353169 Free PMC article.
Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents.
Docherty AR, Shabalin AA, DiBlasi E, Monson E, Mullins N, Adkins DE, Bacanu SA, Bakian AV, Crowell S, Chen D, Darlington TM, Callor WB, Christensen ED, Gray D, Keeshin B, Klein M, Anderson JS, Jerominski L, Hayward C, Porteous DJ, McIntosh A, Li Q, Coon H. Docherty AR, et al. Among authors: christensen ed. Am J Psychiatry. 2020 Oct 1;177(10):917-927. doi: 10.1176/appi.ajp.2020.19101025. Am J Psychiatry. 2020. PMID: 32998551 Free PMC article.
Rare protein-coding variants implicate genes involved in risk of suicide death.
DiBlasi E, Shabalin AA, Monson ET, Keeshin BR, Bakian AV, Kirby AV, Ferris E, Chen D, William N, Gaj E, Klein M, Jerominski L, Callor WB, Christensen E, Smith KR, Fraser A, Yu Z, Gray D; PsychChip Investigators of the Psychiatric Genomics Consortium; Camp NJ, Stahl EA, Li QS, Docherty AR, Coon H. DiBlasi E, et al. Am J Med Genet B Neuropsychiatr Genet. 2021 Dec;186(8):508-520. doi: 10.1002/ajmg.b.32861. Epub 2021 May 27. Am J Med Genet B Neuropsychiatr Genet. 2021. PMID: 34042246 Free PMC article.
Neurexin 1 variants as risk factors for suicide death.
William N, Reissner C, Sargent R, Darlington TM, DiBlasi E, Li QS, Keeshin B, Callor WB, Ferris E, Jerominski L, Smith KR, Christensen ED, Gray DM, Camp NJ, Missler M, Williams ME, Coon H. William N, et al. Among authors: christensen ed. Mol Psychiatry. 2021 Dec;26(12):7436-7445. doi: 10.1038/s41380-021-01190-2. Epub 2021 Jun 25. Mol Psychiatry. 2021. PMID: 34168285 Free PMC article.
Extended familial risk of suicide death is associated with younger age at death and elevated polygenic risk of suicide.
Coon H, Shabalin A, Bakian AV, DiBlasi E, Monson ET, Kirby A, Chen D, Fraser A, Yu Z, Staley M, Callor WB, Christensen ED, Crowell SE, Gray D, Crockett DK, Li QS, Keeshin B, Docherty AR. Coon H, et al. Among authors: christensen ed. Am J Med Genet B Neuropsychiatr Genet. 2022 Apr;189(3-4):60-73. doi: 10.1002/ajmg.b.32890. Epub 2022 Feb 24. Am J Med Genet B Neuropsychiatr Genet. 2022. PMID: 35212135 Free PMC article.
Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
Kimbrel NA, Ashley-Koch AE, Qin XJ, Lindquist JH, Garrett ME, Dennis MF, Hair LP, Huffman JE, Jacobson DA, Madduri RK, Trafton JA, Coon H, Docherty AR, Mullins N, Ruderfer DM, Harvey PD, McMahon BH, Oslin DW, Beckham JC, Hauser ER, Hauser MA; Million Veteran Program Suicide Exemplar Workgroup, the International Suicide Genetics Consortium, the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, and the Veterans Affairs Million Veteran Program. Kimbrel NA, et al. JAMA Psychiatry. 2023 Feb 1;80(2):135-145. doi: 10.1001/jamapsychiatry.2022.3896. JAMA Psychiatry. 2023. PMID: 36515925 Free PMC article.
Whole-genome sequencing analysis of suicide deaths integrating brain-regulatory eQTLs data to identify risk loci and genes.
Han S, DiBlasi E, Monson ET, Shabalin A, Ferris E, Chen D, Fraser A, Yu Z, Staley M, Callor WB, Christensen ED, Crockett DK, Li QS, Willour V, Bakian AV, Keeshin B, Docherty AR, Eilbeck K, Coon H. Han S, et al. Among authors: christensen ed. Mol Psychiatry. 2023 Sep;28(9):3909-3919. doi: 10.1038/s41380-023-02282-x. Epub 2023 Oct 4. Mol Psychiatry. 2023. PMID: 37794117 Free PMC article.
49 results