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Hyaluronan is a natural and effective immunological adjuvant for protein-based vaccines.
Dalla Pietà A, Carpanese D, Grigoletto A, Tosi A, Dalla Santa S, Pedersen GK, Christensen D, Meléndez-Alafort L, Barbieri V, De Benedictis P, Pasut G, Montagner IM, Rosato A. Dalla Pietà A, et al. Among authors: christensen d. Cell Mol Immunol. 2021 May;18(5):1197-1210. doi: 10.1038/s41423-021-00667-y. Epub 2021 Mar 24. Cell Mol Immunol. 2021. PMID: 33762685 Free PMC article.
The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes.
Korsholm KS, Agger EM, Foged C, Christensen D, Dietrich J, Andersen CS, Geisler C, Andersen P. Korsholm KS, et al. Among authors: christensen d. Immunology. 2007 Jun;121(2):216-26. doi: 10.1111/j.1365-2567.2007.02560.x. Epub 2007 Feb 14. Immunology. 2007. PMID: 17302734 Free PMC article.
Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements.
Agger EM, Rosenkrands I, Hansen J, Brahimi K, Vandahl BS, Aagaard C, Werninghaus K, Kirschning C, Lang R, Christensen D, Theisen M, Follmann F, Andersen P. Agger EM, et al. Among authors: christensen d. PLoS One. 2008 Sep 8;3(9):e3116. doi: 10.1371/journal.pone.0003116. PLoS One. 2008. PMID: 18776936 Free PMC article.
Vaccine adjuvants: Why and how.
Christensen D. Christensen D. Hum Vaccin Immunother. 2016 Oct 2;12(10):2709-2711. doi: 10.1080/21645515.2016.1219003. Hum Vaccin Immunother. 2016. PMID: 27551808 Free PMC article.
Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C).
Schmidt ST, Pedersen GK, Neustrup MA, Korsholm KS, Rades T, Andersen P, Foged C, Christensen D. Schmidt ST, et al. Among authors: christensen d. Front Immunol. 2018 Apr 30;9:898. doi: 10.3389/fimmu.2018.00898. eCollection 2018. Front Immunol. 2018. PMID: 29760705 Free PMC article.
Lipid conjugation of TLR7 agonist Resiquimod ensures co-delivery with the liposomal Cationic Adjuvant Formulation 01 (CAF01) but does not enhance immunopotentiation compared to non-conjugated Resiquimod+CAF01.
Wilkinson A, Lattmann E, Roces CB, Pedersen GK, Christensen D, Perrie Y. Wilkinson A, et al. Among authors: christensen d. J Control Release. 2018 Dec 10;291:1-10. doi: 10.1016/j.jconrel.2018.10.002. Epub 2018 Oct 3. J Control Release. 2018. PMID: 30291987 Free article.
Immunocorrelates of CAF family adjuvants.
Pedersen GK, Andersen P, Christensen D. Pedersen GK, et al. Among authors: christensen d. Semin Immunol. 2018 Oct;39:4-13. doi: 10.1016/j.smim.2018.10.003. Epub 2018 Nov 2. Semin Immunol. 2018. PMID: 30396811 Free article. Review.
1,142 results