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Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target.
van Rhijn N, Zhao C, Al-Furaji N, Storer I, Valero C, Gago S, Chown H, Baldin C, Fortune-Grant R, Shuraym HB, Ivanova L, Kniemeyer O, Krüger T, Bignell E, Goldman G, Amich J, Delneri D, Bowyer P, Brakhage A, Haas H, Bromley M. van Rhijn N, et al. Among authors: chown h. Res Sq [Preprint]. 2023 May 30:rs.3.rs-2960526. doi: 10.21203/rs.3.rs-2960526/v1. Res Sq. 2023. PMID: 37398159 Free PMC article. Preprint.
Aspergillus fumigatus Can Display Persistence to the Fungicidal Drug Voriconazole.
Scott J, Valero C, Mato-López Á, Donaldson IJ, Roldán A, Chown H, Van Rhijn N, Lobo-Vega R, Gago S, Furukawa T, Morogovsky A, Ben Ami R, Bowyer P, Osherov N, Fontaine T, Goldman GH, Mellado E, Bromley M, Amich J. Scott J, et al. Among authors: chown h. Microbiol Spectr. 2023 Mar 13;11(2):e0477022. doi: 10.1128/spectrum.04770-22. Online ahead of print. Microbiol Spectr. 2023. PMID: 36912663 Free PMC article.
Publisher Correction: Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment.
Rhodes J, Abdolrasouli A, Dunne K, Sewell TR, Zhang Y, Ballard E, Brackin AP, van Rhijn N, Chown H, Tsitsopoulou A, Posso RB, Chotirmall SH, McElvaney NG, Murphy PG, Talento AF, Renwick J, Dyer PS, Szekely A, Bowyer P, Bromley MJ, Johnson EM, Lewis White P, Warris A, Barton RC, Schelenz S, Rogers TR, Armstrong-James D, Fisher MC. Rhodes J, et al. Among authors: chown h. Nat Microbiol. 2022 Nov;7(11):1944. doi: 10.1038/s41564-022-01160-6. Nat Microbiol. 2022. PMID: 36203089 Free PMC article. No abstract available.
Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment.
Rhodes J, Abdolrasouli A, Dunne K, Sewell TR, Zhang Y, Ballard E, Brackin AP, van Rhijn N, Chown H, Tsitsopoulou A, Posso RB, Chotirmall SH, McElvaney NG, Murphy PG, Talento AF, Renwick J, Dyer PS, Szekely A, Bowyer P, Bromley MJ, Johnson EM, Lewis White P, Warris A, Barton RC, Schelenz S, Rogers TR, Armstrong-James D, Fisher MC. Rhodes J, et al. Among authors: chown h. Nat Microbiol. 2022 May;7(5):663-674. doi: 10.1038/s41564-022-01091-2. Epub 2022 Apr 25. Nat Microbiol. 2022. PMID: 35469019 Free PMC article.