Chow ECY - Search Results

1

3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration.

Wang H, Brown PC, Chow ECY, Ewart L, Ferguson SS, Fitzpatrick S, Freedman BS, Guo GL, Hedrich W, Heyward S, Hickman J, Isoherranen N, Li AP, Liu Q, Mumenthaler SM, Polli J, Proctor WR, Ribeiro A, Wang JY, Wange RL, Huang SM. Wang H, et al. Among authors: chow ecy. Clin Transl Sci. 2021 Sep;14(5):1659-1680. doi: 10.1111/cts.13066. Epub 2021 Jun 16. Clin Transl Sci. 2021. PMID: 33982436 Free PMC article. Review.

2

Disrupted Murine Gut-to-Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models.

Chow EC, Quach HP, Zhang Y, Wang JZ, Evans DC, Li AP, Silva J, Tirona RG, Lai Y, Pang KS. Chow EC, et al. J Pharmacol Exp Ther. 2017 Jan;360(1):174-191. doi: 10.1124/jpet.116.236935. Epub 2016 Oct 27. J Pharmacol Exp Ther. 2017. PMID: 27789682

3

Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters.

Chow EC, Wang JZ, Quach HP, Tang H, Evans DC, Li AP, Silva J, Pang KS. Chow EC, et al. Drug Metab Dispos. 2016 Sep;44(9):1524-35. doi: 10.1124/dmd.116.070060. Epub 2016 Jun 24. Drug Metab Dispos. 2016. PMID: 27342868

4

Alterations in gene expression in vitamin D-deficiency: Down-regulation of liver Cyp7a1 and renal Oat3 in mice.

Quach HP, Noh K, Hoi SY, Bruinsma A, Groothuis GMM, Li AP, Chow ECY, Pang KS. Quach HP, et al. Among authors: chow ecy. Biopharm Drug Dispos. 2018 Feb;39(2):99-115. doi: 10.1002/bdd.2118. Epub 2018 Jan 30. Biopharm Drug Dispos. 2018. PMID: 29243851

5

Why we need proper PBPK models to examine intestine and liver oral drug absorption.

Chow EC, Pang KS. Chow EC, et al. Curr Drug Metab. 2013 Jan;14(1):57-79. Curr Drug Metab. 2013. PMID: 22935069 Review.

6

PBPK modeling of intestinal and liver enzymes and transporters in drug absorption and sequential metabolism.

Fan J, Chen S, Chow EC, Pang KS. Fan J, et al. Curr Drug Metab. 2010 Nov;11(9):743-61. doi: 10.2174/138920010794328931. Curr Drug Metab. 2010. PMID: 21189137 Review.

7

Significance of the Vitamin D Receptor on Crosstalk with Nuclear Receptors and Regulation of Enzymes and Transporters.

Noh K, Chow ECY, Quach HP, Groothuis GMM, Tirona RG, Pang KS. Noh K, et al. Among authors: chow ecy. AAPS J. 2022 Jun 1;24(4):71. doi: 10.1208/s12248-022-00719-9. AAPS J. 2022. PMID: 35650371 Review.

8

Effects of 1alpha,25-dihydroxyvitamin D3 on transporters and enzymes of the rat intestine and kidney in vivo.

Chow EC, Sun H, Khan AA, Groothuis GM, Pang KS. Chow EC, et al. Biopharm Drug Dispos. 2010 Jan;31(1):91-108. doi: 10.1002/bdd.694. Biopharm Drug Dispos. 2010. PMID: 20013813

9

Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat.

Kim YC, Kim IB, Noh CK, Quach HP, Yoon IS, Chow ECY, Kim M, Jin HE, Cho KH, Chung SJ, Pang KS, Maeng HJ. Kim YC, et al. Among authors: chow ecy. J Pharm Sci. 2014 Nov;103(11):3793-3805. doi: 10.1002/jps.24195. Epub 2014 Sep 29. J Pharm Sci. 2014. PMID: 25266751

10

Digitally monitored inhaled therapy: a 'smart' way to manage severe asthma?

Sykes DL, See YY, Chow ECY, Crooks MG, Cummings H, Robinson M, Watkins K, Thompson J, Overton K, Riches C, Faruqi S. Sykes DL, et al. Among authors: chow ecy. J Asthma. 2024 Feb 16:1-6. doi: 10.1080/02770903.2024.2316726. Online ahead of print. J Asthma. 2024. PMID: 38323583

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