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Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart.
Young ME, Brewer RA, Peliciari-Garcia RA, Collins HE, He L, Birky TL, Peden BW, Thompson EG, Ammons BJ, Bray MS, Chatham JC, Wende AR, Yang Q, Chow CW, Martino TA, Gamble KL. Young ME, et al. Among authors: chow cw. J Biol Rhythms. 2014 Aug;29(4):257-76. doi: 10.1177/0748730414543141. J Biol Rhythms. 2014. PMID: 25238855 Free PMC article.
Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression.
Bray MS, Shaw CA, Moore MW, Garcia RA, Zanquetta MM, Durgan DJ, Jeong WJ, Tsai JY, Bugger H, Zhang D, Rohrwasser A, Rennison JH, Dyck JR, Litwin SE, Hardin PE, Chow CW, Chandler MP, Abel ED, Young ME. Bray MS, et al. Among authors: chow cw. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1036-47. doi: 10.1152/ajpheart.01291.2007. Epub 2007 Dec 21. Am J Physiol Heart Circ Physiol. 2008. PMID: 18156197 Free article.
Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock.
Tsai JY, Kienesberger PC, Pulinilkunnil T, Sailors MH, Durgan DJ, Villegas-Montoya C, Jahoor A, Gonzalez R, Garvey ME, Boland B, Blasier Z, McElfresh TA, Nannegari V, Chow CW, Heird WC, Chandler MP, Dyck JR, Bray MS, Young ME. Tsai JY, et al. Among authors: chow cw. J Biol Chem. 2010 Jan 29;285(5):2918-29. doi: 10.1074/jbc.M109.077800. Epub 2009 Nov 25. J Biol Chem. 2010. PMID: 19940111 Free PMC article.
509 results