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A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies.
Ferrara F, Erasmus MF, D'Angelo S, Leal-Lopes C, Teixeira AA, Choudhary A, Honnen W, Calianese D, Huang D, Peng L, Voss JE, Nemazee D, Burton DR, Pinter A, Bradbury ARM. Ferrara F, et al. Among authors: choudhary a. Nat Commun. 2022 Jan 24;13(1):462. doi: 10.1038/s41467-021-27799-z. Nat Commun. 2022. PMID: 35075126 Free PMC article.
Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen.
Choudhary A, Patel D, Honnen W, Lai Z, Prattipati RS, Zheng RB, Hsueh YC, Gennaro ML, Lardizabal A, Restrepo BI, Garcia-Viveros M, Joe M, Bai Y, Shen K, Sahloul K, Spencer JS, Chatterjee D, Broger T, Lowary TL, Pinter A. Choudhary A, et al. J Immunol. 2018 May 1;200(9):3053-3066. doi: 10.4049/jimmunol.1701673. Epub 2018 Apr 2. J Immunol. 2018. PMID: 29610143 Free PMC article.
Detection of lipoarabinomannan in urine and serum of HIV-positive and HIV-negative TB suspects using an improved capture-enzyme linked immuno absorbent assay and gas chromatography/mass spectrometry.
Amin AG, De P, Spencer JS, Brennan PJ, Daum J, Andre BG, Joe M, Bai Y, Laurentius L, Porter MD, Honnen WJ, Choudhary A, Lowary TL, Pinter A, Chatterjee D. Amin AG, et al. Among authors: choudhary a. Tuberculosis (Edinb). 2018 Jul;111:178-187. doi: 10.1016/j.tube.2018.06.004. Epub 2018 Jun 6. Tuberculosis (Edinb). 2018. PMID: 30029905
A Novel Sensitive Immunoassay Targeting the 5-Methylthio-d-Xylofuranose-Lipoarabinomannan Epitope Meets the WHO's Performance Target for Tuberculosis Diagnosis.
Sigal GB, Pinter A, Lowary TL, Kawasaki M, Li A, Mathew A, Tsionsky M, Zheng RB, Plisova T, Shen K, Katsuragi K, Choudhary A, Honnen WJ, Nahid P, Denkinger CM, Broger T. Sigal GB, et al. Among authors: choudhary a. J Clin Microbiol. 2018 Nov 27;56(12):e01338-18. doi: 10.1128/JCM.01338-18. Print 2018 Dec. J Clin Microbiol. 2018. PMID: 30257899 Free PMC article.
Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes.
Magni R, Rruga F, Alsaab FM, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF 3rd, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A. Magni R, et al. Among authors: choudhary a. Sci Rep. 2020 Aug 18;10(1):13944. doi: 10.1038/s41598-020-70669-9. Sci Rep. 2020. PMID: 32811861 Free PMC article.
Vaccination boosts protective responses and counters SARS-CoV-2-induced pathogenic memory B cells.
Mishra PK, Bruiners N, Ukey R, Datta P, Onyuka A, Handler D, Hussain S, Honnen W, Singh S, Guerrini V, Yin Y, Dewald H, Choudhary A, Horton DB, Barrett ES, Roy J, Weiss SH, Fitzgerald-Bocarsly P, Blaser MJ, Carson JL, Panettieri RA Jr, Lardizabal A, Chang TL, Pinter A, Gennaro ML. Mishra PK, et al. Among authors: choudhary a. medRxiv [Preprint]. 2021 May 12:2021.04.11.21255153. doi: 10.1101/2021.04.11.21255153. medRxiv. 2021. PMID: 33880486 Free PMC article. Preprint.
Phosphatidylserine-Targeting Monoclonal Antibodies Exhibit Distinct Biochemical and Cellular Effects on Anti-CD3/CD28-Stimulated T Cell IFN-γ and TNF-α Production.
Calianese D, Kreiss T, Kasikara C, Davra V, Lahey KC, Gadiyar V, Geng K, Singh S, Honnen W, Jaijyan DK, Reichman C, Siekierka J, Gennaro ML, Kotenko SV, Ucker DS, Brekken RA, Pinter A, Birge RB, Choudhary A. Calianese D, et al. Among authors: choudhary a. J Immunol. 2021 Jul 15;207(2):436-448. doi: 10.4049/jimmunol.2000763. Epub 2021 Jul 2. J Immunol. 2021. PMID: 34215655
Highly versatile antibody binding assay for the detection of SARS-CoV-2 infection.
Datta P, Ukey R, Bruiners N, Honnen W, Carayannopoulos MO, Reichman C, Choudhary A, Onyuka A, Handler D, Guerrini V, Mishra PK, Dewald HK, Lardizabal A, Lederer L, Leiser AL, Hussain S, Jagpal SK, Radbel J, Bhowmick T, Horton DB, Barrett ES, Xie YL, Fitzgerald-Bocarsly P, Weiss SH, Woortman M, Parmar H, Roy J, Dominguez-Bello MG, Blaser MJ, Carson JL, Panettieri RA Jr, Libutti SK, Raymond HF, Pinter A, Gennaro ML. Datta P, et al. Among authors: choudhary a. medRxiv [Preprint]. 2021 Jul 14:2021.07.09.21260266. doi: 10.1101/2021.07.09.21260266. medRxiv. 2021. PMID: 34282427 Free PMC article. Updated. Preprint.
CAR-NK Cells Effectively Target SARS-CoV-2-Spike-Expressing Cell Lines In Vitro.
Ma MT, Badeti S, Chen CH, Kim J, Choudhary A, Honnen B, Reichman C, Calianese D, Pinter A, Jiang Q, Shi L, Zhou R, Xu H, Li Q, Gause W, Liu D. Ma MT, et al. Among authors: choudhary a. Front Immunol. 2021 Jul 23;12:652223. doi: 10.3389/fimmu.2021.652223. eCollection 2021. Front Immunol. 2021. PMID: 34367128 Free PMC article.
1,091 results