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A multitope SARS-CoV-2 vaccine provides long-lasting B cell and T cell immunity against Delta and Omicron variants.
Wang CY, Hwang KP, Kuo HK, Peng WJ, Shen YH, Kuo BS, Huang JH, Liu H, Ho YH, Lin F, Ding S, Liu Z, Wu HT, Huang CT, Lee YJ, Liu MC, Yang YC, Lu PL, Tsai HC, Lee CH, Shi ZY, Liu CE, Liao CH, Chang FY, Chen HC, Wang FD, Hou KL, Cheng J, Wang MS, Yang YT, Chiu HC, Jiang MH, Shih HY, Shen HY, Chang PY, Lan YR, Chen CT, Lin YL, Liang JJ, Liao CC, Chou YC, Morris MK, Hanson CV, Guirakhoo F, Hellerstein M, Yu HJ, King CC, Kemp T, Heppner DG, Monath TP. Wang CY, et al. Among authors: chou yc. J Clin Invest. 2022 May 16;132(10):e157707. doi: 10.1172/JCI157707. J Clin Invest. 2022. PMID: 35316221 Free PMC article. Clinical Trial.
Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain.
Huang PH, Tsai HH, Liao BH, Lin YL, Jan JT, Tao MH, Chou YC, Hu CJ, Chen HW. Huang PH, et al. Among authors: chou yc. Hum Vaccin Immunother. 2021 Mar 4;17(3):654-655. doi: 10.1080/21645515.2020.1814098. Epub 2020 Sep 29. Hum Vaccin Immunother. 2021. PMID: 32991231 Free PMC article.
Antibody cocktail effective against variants of SARS-CoV-2.
Liang KH, Chiang PY, Ko SH, Chou YC, Lu RM, Lin HT, Chen WY, Lin YL, Tao MH, Jan JT, Wu HC. Liang KH, et al. Among authors: chou yc. J Biomed Sci. 2021 Nov 23;28(1):80. doi: 10.1186/s12929-021-00777-9. J Biomed Sci. 2021. PMID: 34814920 Free PMC article.
Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models.
Huang HY, Liao HY, Chen X, Wang SW, Cheng CW, Shahed-Al-Mahmud M, Liu YM, Mohapatra A, Chen TH, Lo JM, Wu YM, Ma HH, Chang YH, Tsai HY, Chou YC, Hsueh YP, Tsai CY, Huang PY, Chang SY, Chao TL, Kao HC, Tsai YM, Chen YH, Wu CY, Jan JT, Cheng TR, Lin KI, Ma C, Wong CH. Huang HY, et al. Among authors: chou yc. Sci Transl Med. 2022 Apr 6;14(639):eabm0899. doi: 10.1126/scitranslmed.abm0899. Epub 2022 Apr 6. Sci Transl Med. 2022. PMID: 35230146 Free PMC article.
A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants.
Lee IJ, Sun CP, Wu PY, Lan YH, Wang IH, Liu WC, Yuan JP, Chang YW, Tseng SC, Tsung SI, Chou YC, Kumari M, Lin YS, Chen HF, Chen TY, Lin CC, Chiu CW, Hsieh CH, Chuang CY, Cheng CM, Lin HT, Chen WY, Hsu FF, Hong MH, Liao CC, Chang CS, Liang JJ, Ma HH, Chiang MT, Liao HN, Ko HY, Chen LY, Ko YA, Yu PY, Yang TJ, Chiang PC, Hsu ST, Lin YL, Lee CC, Wu HC, Tao MH. Lee IJ, et al. Among authors: chou yc. J Biomed Sci. 2022 Jul 7;29(1):49. doi: 10.1186/s12929-022-00830-1. J Biomed Sci. 2022. PMID: 35799178 Free PMC article.
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.
Huang KA, Chen X, Mohapatra A, Nguyen HTV, Schimanski L, Tan TK, Rijal P, Vester SK, Hills RA, Howarth M, Keeffe JR, Cohen AA, Kakutani LM, Wu YM, Shahed-Al-Mahmud M, Chou YC, Bjorkman PJ, Townsend AR, Ma C. Huang KA, et al. Among authors: chou yc. Nat Commun. 2023 Jan 19;14(1):311. doi: 10.1038/s41467-023-35949-8. Nat Commun. 2023. PMID: 36658148 Free PMC article.
889 results