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Defining the challenges and opportunities for using patient-derived models in prostate cancer research.
Brennen WN, Le Magnen C, Karkampouna S, Anselmino N, Bock N, Choo N, Clark AK, Coleman IM, Dolgos R, Ferguson AM, Goode DL, Krutihof-de Julio M, Navone NM, Nelson PS, O'Neill E, Porter LH, Ranasinghe W, Sunada T, Williams ED, Butler LM, Corey E, van Weerden WM, Taylor RA, Risbridger GP, Lawrence MG. Brennen WN, et al. Among authors: choo n. Prostate. 2024 May;84(7):623-635. doi: 10.1002/pros.24682. Epub 2024 Mar 7. Prostate. 2024. PMID: 38450798 Free article. Review.
High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids.
Choo N, Ramm S, Luu J, Winter JM, Selth LA, Dwyer AR, Frydenberg M, Grummet J, Sandhu S, Hickey TE, Tilley WD, Taylor RA, Risbridger GP, Lawrence MG, Simpson KJ. Choo N, et al. SLAS Discov. 2021 Oct;26(9):1107-1124. doi: 10.1177/24725552211020668. Epub 2021 Jun 11. SLAS Discov. 2021. PMID: 34111999 Free PMC article.
CX-5461 Sensitizes DNA Damage Repair-proficient Castrate-resistant Prostate Cancer to PARP Inhibition.
Lawrence MG, Porter LH, Choo N, Pook D, Grummet JP, Pezaro CJ, Sandhu S, Ramm S, Luu J, Bakshi A, Goode DL, Sanij E, Pearson RB, Hannan RD, Simpson KJ, Taylor RA, Risbridger GP, Furic L. Lawrence MG, et al. Among authors: choo n. Mol Cancer Ther. 2021 Nov;20(11):2140-2150. doi: 10.1158/1535-7163.MCT-20-0932. Epub 2021 Aug 19. Mol Cancer Ther. 2021. PMID: 34413130
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology.
Risbridger GP, Clark AK, Porter LH, Toivanen R, Bakshi A, Lister NL, Pook D, Pezaro CJ, Sandhu S, Keerthikumar S, Quezada Urban R, Papargiris M, Kraska J, Madsen HB, Wang H, Richards MG, Niranjan B, O'Dea S, Teng L, Wheelahan W, Li Z, Choo N, Ouyang JF, Thorne H, Devereux L, Hicks RJ, Sengupta S, Harewood L, Iddawala M, Azad AA, Goad J, Grummet J, Kourambas J, Kwan EM, Moon D, Murphy DG, Pedersen J, Clouston D, Norden S, Ryan A, Furic L, Goode DL, Frydenberg M, Lawrence MG, Taylor RA. Risbridger GP, et al. Among authors: choo n. Nat Commun. 2021 Aug 19;12(1):5049. doi: 10.1038/s41467-021-25175-5. Nat Commun. 2021. PMID: 34413304 Free PMC article.
New approaches to targeting epigenetic regulation in prostate cancer.
Thompson D, Choo N, Bolton DM, Lawrentschuk N, Risbridger GP, Lawrence MG, Taylor RA. Thompson D, et al. Among authors: choo n. Curr Opin Urol. 2022 Sep 1;32(5):472-480. doi: 10.1097/MOU.0000000000001027. Epub 2022 Jul 22. Curr Opin Urol. 2022. PMID: 35869742 Review.
Integration of genome-scale data identifies candidate sleep regulators.
Lee YY, Endale M, Wu G, Ruben MD, Francey LJ, Morris AR, Choo NY, Anafi RC, Smith DF, Liu AC, Hogenesch JB. Lee YY, et al. Among authors: choo ny. Sleep. 2023 Feb 8;46(2):zsac279. doi: 10.1093/sleep/zsac279. Sleep. 2023. PMID: 36462188 Free PMC article.
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