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Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer.
Philips GM, Chan IS, Swiderska M, Schroder VT, Guy C, Karaca GF, Moylan C, Venkatraman T, Feuerlein S, Syn WK, Jung Y, Witek RP, Choi S, Michelotti GA, Rangwala F, Merkle E, Lascola C, Diehl AM. Philips GM, et al. Among authors: choi s. PLoS One. 2011;6(9):e23943. doi: 10.1371/journal.pone.0023943. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912653 Free PMC article.
Hedgehog signaling in the liver.
Omenetti A, Choi S, Michelotti G, Diehl AM. Omenetti A, et al. Among authors: choi s. J Hepatol. 2011 Feb;54(2):366-73. doi: 10.1016/j.jhep.2010.10.003. Epub 2010 Oct 14. J Hepatol. 2011. PMID: 21093090 Free PMC article. Review.
Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.
Syn WK, Jung Y, Omenetti A, Abdelmalek M, Guy CD, Yang L, Wang J, Witek RP, Fearing CM, Pereira TA, Teaberry V, Choi SS, Conde-Vancells J, Karaca GF, Diehl AM. Syn WK, et al. Among authors: choi ss. Gastroenterology. 2009 Oct;137(4):1478-1488.e8. doi: 10.1053/j.gastro.2009.06.051. Epub 2009 Jul 3. Gastroenterology. 2009. PMID: 19577569 Free PMC article.
Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis.
Choi SS, Omenetti A, Witek RP, Moylan CA, Syn WK, Jung Y, Yang L, Sudan DL, Sicklick JK, Michelotti GA, Rojkind M, Diehl AM. Choi SS, et al. Am J Physiol Gastrointest Liver Physiol. 2009 Dec;297(6):G1093-106. doi: 10.1152/ajpgi.00292.2009. Epub 2009 Oct 8. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19815628 Free PMC article.
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