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Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth.
Kim W, Lee S, Kim HS, Song M, Cha YH, Kim YH, Shin J, Lee ES, Joo Y, Song JJ, Choi EJ, Choi JW, Lee J, Kang M, Yook JI, Lee MG, Kim YS, Paik S, Kim HH. Kim W, et al. Among authors: choi jw, choi ej. Genome Res. 2018 Jan 11;28(3):374-82. doi: 10.1101/gr.223891.117. Online ahead of print. Genome Res. 2018. PMID: 29326299 Free PMC article.
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
Kim HK, Song M, Lee J, Menon AV, Jung S, Kang YM, Choi JW, Woo E, Koh HC, Nam JW, Kim H. Kim HK, et al. Among authors: choi jw. Nat Methods. 2017 Feb;14(2):153-159. doi: 10.1038/nmeth.4104. Epub 2016 Dec 19. Nat Methods. 2017. PMID: 27992409
Establishment of a platform of non-small-cell lung cancer patient-derived xenografts with clinical and genomic annotation.
Kang HN, Choi JW, Shim HS, Kim J, Kim DJ, Lee CY, Hong MH, Park SY, Park AY, Shin EJ, Lee SY, Pyo KH, Yun MR, Choi HM, Lee SS, Kim SY, Lee H, Paik S, Cho BC, Lee JG, Kim HR. Kang HN, et al. Among authors: choi jw, choi hm. Lung Cancer. 2018 Oct;124:168-178. doi: 10.1016/j.lungcan.2018.08.008. Epub 2018 Aug 11. Lung Cancer. 2018. PMID: 30268457
Mouse-human co-clinical trials demonstrate superior anti-tumour effects of buparlisib (BKM120) and cetuximab combination in squamous cell carcinoma of head and neck.
Kim HR, Kang HN, Yun MR, Ju KY, Choi JW, Jung DM, Pyo KH, Hong MH, Ahn MJ, Sun JM, Kim HS, Kim J, Yoo J, Kim KR, Koh YW, Kim SH, Choi EC, Yoon SO, Shim HS, Paik S, Kim TM, Cho BC. Kim HR, et al. Among authors: choi ec, choi jw. Br J Cancer. 2020 Dec;123(12):1720-1729. doi: 10.1038/s41416-020-01074-2. Epub 2020 Sep 23. Br J Cancer. 2020. PMID: 32963347 Free PMC article. Clinical Trial.
3,528 results