Chocron ES - Search Results

1

Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity.

Giżyńska M, Witkowska J, Karpowicz P, Rostankowski R, Chocron ES, Pickering AM, Osmulski P, Gaczynska M, Jankowska E. Giżyńska M, et al. Among authors: chocron es. J Med Chem. 2019 Jan 10;62(1):359-370. doi: 10.1021/acs.jmedchem.8b01025. Epub 2018 Dec 3. J Med Chem. 2019. PMID: 30452262 Free PMC article.

2

Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer's-like pathology in mouse and fly APP overexpression models.

Chocron ES, Munkácsy E, Kim HS, Karpowicz P, Jiang N, Van Skike CE, DeRosa N, Banh AQ, Palavicini JP, Wityk P, Kalinowski L, Galvan V, Osmulski PA, Jankowska E, Gaczynska M, Pickering AM. Chocron ES, et al. Sci Adv. 2022 Jun 10;8(23):eabk2252. doi: 10.1126/sciadv.abk2252. Epub 2022 Jun 8. Sci Adv. 2022. PMID: 35675410 Free PMC article.

3

Cause or casualty: The role of mitochondrial DNA in aging and age-associated disease.

Chocron ES, Munkácsy E, Pickering AM. Chocron ES, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):285-297. doi: 10.1016/j.bbadis.2018.09.035. Epub 2018 Nov 9. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30419337 Free PMC article. Review.

4

Neuronal-specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age-related cognitive decline.

Munkácsy E, Chocron ES, Quintanilla L, Gendron CM, Pletcher SD, Pickering AM. Munkácsy E, et al. Among authors: chocron es. Aging Cell. 2019 Oct;18(5):e13005. doi: 10.1111/acel.13005. Epub 2019 Jul 23. Aging Cell. 2019. PMID: 31334599 Free PMC article.

5

Mitochondrial TrxR2 regulates metabolism and protects from metabolic disease through enhanced TCA and ETC function.

Chocron ES, Mdaki K, Jiang N, Cropper J, Pickering AM. Chocron ES, et al. Commun Biol. 2022 May 16;5(1):467. doi: 10.1038/s42003-022-03405-w. Commun Biol. 2022. PMID: 35577894 Free PMC article.

6

Gut- and oral-dysbiosis differentially impact spinal- and bulbar-onset ALS, predicting ALS severity and potentially determining the location of disease onset.

Kim HS, Son J, Lee D, Tsai J, Wang D, Chocron ES, Jeong S, Kittrell P, Murchison CF, Kennedy RE, Tobon A, Jackson CE, Pickering AM. Kim HS, et al. Among authors: chocron es. BMC Neurol. 2022 Feb 21;22(1):62. doi: 10.1186/s12883-022-02586-5. BMC Neurol. 2022. PMID: 35189854 Free PMC article.

7

The trifunctional protein mediates thyroid hormone receptor-dependent stimulation of mitochondria metabolism.

Chocron ES, Sayre NL, Holstein D, Saelim N, Ibdah JA, Dong LQ, Zhu X, Cheng SY, Lechleiter JD. Chocron ES, et al. Mol Endocrinol. 2012 Jul;26(7):1117-28. doi: 10.1210/me.2011-1348. Epub 2012 May 8. Mol Endocrinol. 2012. PMID: 22570332 Free PMC article.

8

Germline mutations in TMEM127 confer susceptibility to pheochromocytoma.

Qin Y, Yao L, King EE, Buddavarapu K, Lenci RE, Chocron ES, Lechleiter JD, Sass M, Aronin N, Schiavi F, Boaretto F, Opocher G, Toledo RA, Toledo SP, Stiles C, Aguiar RC, Dahia PL. Qin Y, et al. Among authors: chocron es. Nat Genet. 2010 Mar;42(3):229-33. doi: 10.1038/ng.533. Epub 2010 Feb 14. Nat Genet. 2010. PMID: 20154675 Free PMC article.

9

Inhibition of apoptotic potency by ligand stimulated thyroid hormone receptors located in mitochondria.

Saelim N, Holstein D, Chocron ES, Camacho P, Lechleiter JD. Saelim N, et al. Among authors: chocron es. Apoptosis. 2007 Oct;12(10):1781-94. doi: 10.1007/s10495-007-0109-1. Apoptosis. 2007. PMID: 17701361

10

PrimPol, an archaic primase/polymerase operating in human cells.

García-Gómez S, Reyes A, Martínez-Jiménez MI, Chocrón ES, Mourón S, Terrados G, Powell C, Salido E, Méndez J, Holt IJ, Blanco L. García-Gómez S, et al. Among authors: chocron es. Mol Cell. 2013 Nov 21;52(4):541-53. doi: 10.1016/j.molcel.2013.09.025. Epub 2013 Oct 24. Mol Cell. 2013. PMID: 24207056 Free PMC article.

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