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Missense mutation of SPAST protein (I344K) results in loss of ATPase activity and prolonged the half-life, implicated in autosomal dominant hereditary spastic paraplegia.
Lim JH, Kang HM, Jung HR, Kim DS, Noh KH, Chang TK, Kim BJ, Sung DH, Cho HS, Chung KS, Kim NS, Jung CR. Lim JH, et al. Among authors: cho hs. Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3221-3233. doi: 10.1016/j.bbadis.2018.07.009. Epub 2018 Jul 11. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30006150 Free article.
A new experimental model to study human drug responses.
Noh KH, Kang HM, Oh SJ, Lee JY, Kim DH, Kim M, Chung KS, Son MY, Kim DS, Cho HS, Lee J, Lee DG, Lim JH, Jung CR. Noh KH, et al. Among authors: cho hs. Biofabrication. 2020 Sep 25;12(4):045029. doi: 10.1088/1758-5090/abb652. Biofabrication. 2020. PMID: 32975216
The development of a functional human small intestinal epithelium model for drug absorption.
Kwon O, Jung KB, Lee KR, Son YS, Lee H, Kim JJ, Kim K, Lee S, Song YK, Jung J, Park K, Kim DS, Son MJ, Lee MO, Han TS, Cho HS, Oh SJ, Chung H, Kim SH, Chung KS, Kim J, Jung CR, Son MY. Kwon O, et al. Among authors: cho hs. Sci Adv. 2021 Jun 2;7(23):eabh1586. doi: 10.1126/sciadv.abh1586. Print 2021 Jun. Sci Adv. 2021. PMID: 34078609 Free article.
Development of a quantitative prediction algorithm for target organ-specific similarity of human pluripotent stem cell-derived organoids and cells.
Lee MO, Lee SG, Jung CR, Son YS, Ryu JW, Jung KB, Ahn JH, Oh JH, Lee HA, Lim JH, Kim J, Jang I, Choi J, Jung J, Park K, Lee B, Kim DS, Son MY, Cho HS. Lee MO, et al. Among authors: cho hs. Nat Commun. 2021 Jul 23;12(1):4492. doi: 10.1038/s41467-021-24746-w. Nat Commun. 2021. PMID: 34301945 Free PMC article.
1,155 results