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Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs.
Zhou Z, Ma ML, Chan RWY, Lam WKJ, Peng W, Gai W, Hu X, Ding SC, Ji L, Zhou Q, Cheung PPH, Yu SCY, Teoh JYC, Szeto CC, Wong J, Wong VWS, Wong GLH, Chan SL, Hui EP, Ma BBY, Chan ATC, Chiu RWK, Chan KCA, Lo YMD, Jiang P. Zhou Z, et al. Among authors: chiu rwk. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2220982120. doi: 10.1073/pnas.2220982120. Epub 2023 Apr 19. Proc Natl Acad Sci U S A. 2023. PMID: 37075072 Free PMC article.
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing.
Chan KC, Jiang P, Chan CW, Sun K, Wong J, Hui EP, Chan SL, Chan WC, Hui DS, Ng SS, Chan HL, Wong CS, Ma BB, Chan AT, Lai PB, Sun H, Chiu RW, Lo YM. Chan KC, et al. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18761-8. doi: 10.1073/pnas.1313995110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191000 Free PMC article.
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA.
Serpas L, Chan RWY, Jiang P, Ni M, Sun K, Rashidfarrokhi A, Soni C, Sisirak V, Lee WS, Cheng SH, Peng W, Chan KCA, Chiu RWK, Reizis B, Lo YMD. Serpas L, et al. Among authors: chiu rwk. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):641-649. doi: 10.1073/pnas.1815031116. Epub 2018 Dec 28. Proc Natl Acad Sci U S A. 2019. PMID: 30593563 Free PMC article.
Epigenetic analysis of cell-free DNA by fragmentomic profiling.
Zhou Q, Kang G, Jiang P, Qiao R, Lam WKJ, Yu SCY, Ma ML, Ji L, Cheng SH, Gai W, Peng W, Shang H, Chan RWY, Chan SL, Wong GLH, Hiraki LT, Volpi S, Wong VWS, Wong J, Chiu RWK, Chan KCA, Lo YMD. Zhou Q, et al. Among authors: chiu rwk. Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2209852119. doi: 10.1073/pnas.2209852119. Epub 2022 Oct 26. Proc Natl Acad Sci U S A. 2022. PMID: 36288287 Free PMC article.
206 results