Chiu ML - Search Results

1

A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.

Moores SL, Chiu ML, Bushey BS, Chevalier K, Luistro L, Dorn K, Brezski RJ, Haytko P, Kelly T, Wu SJ, Martin PL, Neijssen J, Parren PW, Schuurman J, Attar RM, Laquerre S, Lorenzi MV, Anderson GM. Moores SL, et al. Among authors: chiu ml. Cancer Res. 2016 Jul 1;76(13):3942-53. doi: 10.1158/0008-5472.CAN-15-2833. Epub 2016 May 23. Cancer Res. 2016. PMID: 27216193

2

Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody.

Jarantow SW, Bushey BS, Pardinas JR, Boakye K, Lacy ER, Sanders R, Sepulveda MA, Moores SL, Chiu ML. Jarantow SW, et al. Among authors: chiu ml. J Biol Chem. 2015 Oct 9;290(41):24689-704. doi: 10.1074/jbc.M115.651653. Epub 2015 Aug 10. J Biol Chem. 2015. PMID: 26260789 Free PMC article.

3

Cross-arm binding efficiency of an EGFR x c-Met bispecific antibody.

Zheng S, Moores S, Jarantow S, Pardinas J, Chiu M, Zhou H, Wang W. Zheng S, et al. MAbs. 2016;8(3):551-61. doi: 10.1080/19420862.2015.1136762. Epub 2016 Jan 13. MAbs. 2016. PMID: 26761634 Free PMC article.

4

An efficient process of generating bispecific antibodies via controlled Fab-arm exchange using culture supernatants.

Paul S, Connor J, Nesspor T, Haytko P, Boakye K, Chiu ML, Jiang H. Paul S, et al. Among authors: chiu ml. Protein Expr Purif. 2016 May;121:133-40. doi: 10.1016/j.pep.2016.01.014. Epub 2016 Jan 27. Protein Expr Purif. 2016. PMID: 26826313

5

Fc-mediated activity of EGFR x c-Met bispecific antibody JNJ-61186372 enhanced killing of lung cancer cells.

Grugan KD, Dorn K, Jarantow SW, Bushey BS, Pardinas JR, Laquerre S, Moores SL, Chiu ML. Grugan KD, et al. Among authors: chiu ml. MAbs. 2017 Jan;9(1):114-126. doi: 10.1080/19420862.2016.1249079. Epub 2016 Oct 27. MAbs. 2017. PMID: 27786612 Free PMC article.

6

Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models.

Labrijn AF, Meesters JI, Bunce M, Armstrong AA, Somani S, Nesspor TC, Chiu ML, Altintaş I, Verploegen S, Schuurman J, Parren PWHI. Labrijn AF, et al. Among authors: chiu ml. Sci Rep. 2017 May 30;7(1):2476. doi: 10.1038/s41598-017-02823-9. Sci Rep. 2017. PMID: 28559564 Free PMC article.

7

Influence of the bispecific antibody IgG subclass on T cell redirection.

Kapelski S, Cleiren E, Attar RM, Philippar U, Häsler J, Chiu ML. Kapelski S, et al. Among authors: chiu ml. MAbs. 2019 Aug/Sep;11(6):1012-1024. doi: 10.1080/19420862.2019.1624464. Epub 2019 Jun 26. MAbs. 2019. PMID: 31242061 Free PMC article.

8

Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.

Tam SH, McCarthy SG, Armstrong AA, Somani S, Wu SJ, Liu X, Gervais A, Ernst R, Saro D, Decker R, Luo J, Gilliland GL, Chiu ML, Scallon BJ. Tam SH, et al. Among authors: chiu ml. Antibodies (Basel). 2017 Sep 1;6(3):12. doi: 10.3390/antib6030012. Antibodies (Basel). 2017. PMID: 31548527 Free PMC article.

9

Characterization of a Novel Bispecific Antibody That Activates T Cells In Vitro and Slows Tumor Growth In Vivo.

Chornoguz O, Leettola CN, Leander K, Brosnan K, Emmell E, Chiu ML, Santulli-Marotto S. Chornoguz O, et al. Among authors: chiu ml. Monoclon Antib Immunodiagn Immunother. 2019 Dec;38(6):242-254. doi: 10.1089/mab.2019.0035. Monoclon Antib Immunodiagn Immunother. 2019. PMID: 31825302 Free PMC article.

10

Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.

Neijssen J, Cardoso RMF, Chevalier KM, Wiegman L, Valerius T, Anderson GM, Moores SL, Schuurman J, Parren PWHI, Strohl WR, Chiu ML. Neijssen J, et al. Among authors: chiu ml. J Biol Chem. 2021 Jan-Jun;296:100641. doi: 10.1016/j.jbc.2021.100641. Epub 2021 Apr 8. J Biol Chem. 2021. PMID: 33839159 Free PMC article.

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