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5,432 results

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Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Liew F, Efstathiou C, Fontanella S, Richardson M, Saunders R, Swieboda D, Sidhu JK, Ascough S, Moore SC, Mohamed N, Nunag J, King C, Leavy OC, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Harris VC, Houchen-Wolloff L, Greening NJ, Lone NI, Thorpe M, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard LS, Wootton DG, Quint JK, de Silva TI, Ho A, Chiu C, Harrison EM, Greenhalf W, Baillie JK, Semple MG, Turtle L, Evans RA, Wain LV, Brightling C, Thwaites RS, Openshaw PJM; PHOSP-COVID collaborative group; ISARIC investigators. Liew F, et al. Among authors: chiu c. Nat Immunol. 2024 Apr;25(4):607-621. doi: 10.1038/s41590-024-01778-0. Epub 2024 Apr 8. Nat Immunol. 2024. PMID: 38589621 Free PMC article.
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19.
Thwaites RS, Sanchez Sevilla Uruchurtu A, Siggins MK, Liew F, Russell CD, Moore SC, Fairfield C, Carter E, Abrams S, Short CE, Thaventhiran T, Bergstrom E, Gardener Z, Ascough S, Chiu C, Docherty AB, Hunt D, Crow YJ, Solomon T, Taylor GP, Turtle L, Harrison EM, Dunning J, Semple MG, Baillie JK, Openshaw PJ; ISARIC4C investigators. Thwaites RS, et al. Among authors: chiu c. Sci Immunol. 2021 Mar 10;6(57):eabg9873. doi: 10.1126/sciimmunol.abg9873. Sci Immunol. 2021. PMID: 33692097 Free PMC article.
Protective and dysregulated T cell immunity in RSV infection.
Openshaw PJ, Chiu C. Openshaw PJ, et al. Among authors: chiu c. Curr Opin Virol. 2013 Aug;3(4):468-74. doi: 10.1016/j.coviro.2013.05.005. Epub 2013 Jun 25. Curr Opin Virol. 2013. PMID: 23806514 Free PMC article. Review.
Protective and Harmful Immunity to RSV Infection.
Openshaw PJM, Chiu C, Culley FJ, Johansson C. Openshaw PJM, et al. Among authors: chiu c. Annu Rev Immunol. 2017 Apr 26;35:501-532. doi: 10.1146/annurev-immunol-051116-052206. Epub 2017 Feb 6. Annu Rev Immunol. 2017. PMID: 28226227 Review.
Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults.
Wagstaffe HR, Thwaites RS, Reynaldi A, Sidhu JK, McKendry R, Ascough S, Papargyris L, Collins AM, Xu J, Lemm NM, Siggins MK, Chain BM, Killingley B, Kalinova M, Mann A, Catchpole A, Davenport MP, Openshaw PJM, Chiu C. Wagstaffe HR, et al. Among authors: chiu c. Sci Immunol. 2024 Sep 2;9(92):eadj9285. doi: 10.1126/sciimmunol.adj9285. Epub 2024 Feb 9. Sci Immunol. 2024. PMID: 38335268
Controlled Human Infection Challenge Studies with RSV.
Dayananda P, Chiu C, Openshaw P. Dayananda P, et al. Among authors: chiu c. Curr Top Microbiol Immunol. 2022 Jun 16. doi: 10.1007/82_2022_257. Online ahead of print. Curr Top Microbiol Immunol. 2022. PMID: 35704096
Current concepts and progress in RSV vaccine development.
Guvenel AK, Chiu C, Openshaw PJ. Guvenel AK, et al. Among authors: chiu c. Expert Rev Vaccines. 2014 Mar;13(3):333-44. doi: 10.1586/14760584.2014.878653. Epub 2014 Jan 9. Expert Rev Vaccines. 2014. PMID: 24405366 Free PMC article. Review.
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults.
Killingley B, Mann AJ, Kalinova M, Boyers A, Goonawardane N, Zhou J, Lindsell K, Hare SS, Brown J, Frise R, Smith E, Hopkins C, Noulin N, Löndt B, Wilkinson T, Harden S, McShane H, Baillet M, Gilbert A, Jacobs M, Charman C, Mande P, Nguyen-Van-Tam JS, Semple MG, Read RC, Ferguson NM, Openshaw PJ, Rapeport G, Barclay WS, Catchpole AP, Chiu C. Killingley B, et al. Among authors: chiu c. Nat Med. 2022 May;28(5):1031-1041. doi: 10.1038/s41591-022-01780-9. Epub 2022 Mar 31. Nat Med. 2022. PMID: 35361992 Clinical Trial.
5,432 results