Chiti F - Search Results

1

Isolation and characterization of soluble human full-length TDP-43 associated with neurodegeneration.

Vivoli Vega M, Nigro A, Luti S, Capitini C, Fani G, Gonnelli L, Boscaro F, Chiti F. Vivoli Vega M, et al. Among authors: chiti f. FASEB J. 2019 Oct;33(10):10780-10793. doi: 10.1096/fj.201900474R. Epub 2019 Jul 9. FASEB J. 2019. PMID: 31287959

., Nigro, A., Luti, S., Capitini, C., Fani, G., Gonnelli, L., Boscaro, F., Chiti, F. Isolation and characterization of soluble human full-length TDP-43 associated with neurodegeneration....

., Nigro, A., Luti, S., Capitini, C., Fani, G., Gonnelli, L., Boscaro, F., Chiti, F. Isolation and characterization of …

2

TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells.

Capitini C, Conti S, Perni M, Guidi F, Cascella R, De Poli A, Penco A, Relini A, Cecchi C, Chiti F. Capitini C, et al. Among authors: chiti f. PLoS One. 2014 Jan 30;9(1):e86720. doi: 10.1371/journal.pone.0086720. eCollection 2014. PLoS One. 2014. PMID: 24497973 Free PMC article.

3

Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions.

Di Natale C, Scognamiglio PL, Cascella R, Cecchi C, Russo A, Leone M, Penco A, Relini A, Federici L, Di Matteo A, Chiti F, Vitagliano L, Marasco D. Di Natale C, et al. Among authors: chiti f. FASEB J. 2015 Sep;29(9):3689-701. doi: 10.1096/fj.14-269522. Epub 2015 May 14. FASEB J. 2015. PMID: 25977257

4

The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis.

Del Poggetto E, Chiti F, Bemporad F. Del Poggetto E, et al. Among authors: chiti f. Sci Rep. 2015 Jul 31;5:12332. doi: 10.1038/srep12332. Sci Rep. 2015. PMID: 26227615 Free PMC article.

5

Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies.

Cascella R, Capitini C, Fani G, Dobson CM, Cecchi C, Chiti F. Cascella R, et al. Among authors: chiti f. J Biol Chem. 2016 Sep 9;291(37):19437-48. doi: 10.1074/jbc.M116.737726. Epub 2016 Jul 21. J Biol Chem. 2016. PMID: 27445339 Free PMC article.

6

Very rapid amyloid fibril formation by a bacterial lipase in the absence of a detectable lag phase.

Rashno F, Khajeh K, Capitini C, Sajedi RH, Shokri MM, Chiti F. Rashno F, et al. Among authors: chiti f. Biochim Biophys Acta Proteins Proteom. 2017 Jun;1865(6):652-663. doi: 10.1016/j.bbapap.2017.03.004. Epub 2017 Mar 16. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 28315735

7

Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy.

Cascella R, Fani G, Capitini C, Rusmini P, Poletti A, Cecchi C, Chiti F. Cascella R, et al. Among authors: chiti f. FASEB J. 2017 Dec;31(12):5609-5624. doi: 10.1096/fj.201700292RR. Epub 2017 Aug 25. FASEB J. 2017. PMID: 28842427 Free article.

., Fani, G., Capitini, C., Rusmini, P., Poletti, A., Cecchi, C., Chiti, F. Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy....

., Fani, G., Capitini, C., Rusmini, P., Poletti, A., Cecchi, C., Chiti, F. Quantitative assessment of the degradation of aggre …

8

Toxic HypF-N Oligomers Selectively Bind the Plasma Membrane to Impair Cell Adhesion Capability.

Oropesa-Nuñez R, Keshavan S, Dante S, Diaspro A, Mannini B, Capitini C, Cecchi C, Stefani M, Chiti F, Canale C. Oropesa-Nuñez R, et al. Among authors: chiti f. Biophys J. 2018 Mar 27;114(6):1357-1367. doi: 10.1016/j.bpj.2018.02.003. Biophys J. 2018. PMID: 29590593 Free PMC article.

9

Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers.

Patel JR, Xu Y, Capitini C, Chiti F, De Simone A. Patel JR, et al. Among authors: chiti f. Biomol NMR Assign. 2018 Oct;12(2):273-277. doi: 10.1007/s12104-018-9822-7. Epub 2018 May 21. Biomol NMR Assign. 2018. PMID: 29786756 Free PMC article.

10

Structural differences between toxic and nontoxic HypF-N oligomers.

Capitini C, Patel JR, Natalello A, D'Andrea C, Relini A, Jarvis JA, Birolo L, Peduzzo A, Vendruscolo M, Matteini P, Dobson CM, De Simone A, Chiti F. Capitini C, et al. Among authors: chiti f. Chem Commun (Camb). 2018 Aug 11;54(62):8637-8640. doi: 10.1039/c8cc03446j. Epub 2018 Jul 18. Chem Commun (Camb). 2018. PMID: 30020284

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