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Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.
Hu H, Gehart H, Artegiani B, LÖpez-Iglesias C, Dekkers F, Basak O, van Es J, Chuva de Sousa Lopes SM, Begthel H, Korving J, van den Born M, Zou C, Quirk C, Chiriboga L, Rice CM, Ma S, Rios A, Peters PJ, de Jong YP, Clevers H. Hu H, et al. Among authors: chiriboga l. Cell. 2018 Nov 29;175(6):1591-1606.e19. doi: 10.1016/j.cell.2018.11.013. Cell. 2018. PMID: 30500538 Free article.
Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes.
Michailidis E, Vercauteren K, Mancio-Silva L, Andrus L, Jahan C, Ricardo-Lax I, Zou C, Kabbani M, Park P, Quirk C, Pyrgaki C, Razooky B, Verhoye L, Zoluthkin I, Lu WY, Forbes SJ, Chiriboga L, Theise ND, Herzog RW, Suemizu H, Schneider WM, Shlomai A, Meuleman P, Bhatia SN, Rice CM, de Jong YP. Michailidis E, et al. Among authors: chiriboga l. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1678-1688. doi: 10.1073/pnas.1919035117. Epub 2020 Jan 8. Proc Natl Acad Sci U S A. 2020. PMID: 31915293 Free PMC article.
Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells.
Billerbeck E, Mommersteeg MC, Shlomai A, Xiao JW, Andrus L, Bhatta A, Vercauteren K, Michailidis E, Dorner M, Krishnan A, Charlton MR, Chiriboga L, Rice CM, de Jong YP. Billerbeck E, et al. Among authors: chiriboga l. J Hepatol. 2016 Aug;65(2):334-43. doi: 10.1016/j.jhep.2016.04.022. Epub 2016 May 2. J Hepatol. 2016. PMID: 27151182 Free PMC article.
Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice.
Kabbani M, Michailidis E, Steensels S, Fulmer CG, Luna JM, Le Pen J, Tardelli M, Razooky B, Ricardo-Lax I, Zou C, Zeck B, Stenzel AF, Quirk C, Foquet L, Ashbrook AW, Schneider WM, Belkaya S, Lalazar G, Liang Y, Pittman M, Devisscher L, Suemizu H, Theise ND, Chiriboga L, Cohen DE, Copenhaver R, Grompe M, Meuleman P, Ersoy BA, Rice CM, de Jong YP. Kabbani M, et al. Among authors: chiriboga l. Cell Rep. 2022 Sep 13;40(11):111321. doi: 10.1016/j.celrep.2022.111321. Cell Rep. 2022. PMID: 36103835 Free article.
Experimental Variables that Affect Human Hepatocyte AAV Transduction in Liver Chimeric Mice.
Zou C, Vercauteren KOA, Michailidis E, Kabbani M, Zoluthkin I, Quirk C, Chiriboga L, Yazicioglu M, Anguela XM, Meuleman P, High KA, Herzog RW, de Jong YP. Zou C, et al. Among authors: chiriboga l. Mol Ther Methods Clin Dev. 2020 Jun 2;18:189-198. doi: 10.1016/j.omtm.2020.05.033. eCollection 2020 Sep 11. Mol Ther Methods Clin Dev. 2020. PMID: 32637450 Free PMC article.
Broadly neutralizing antibodies abrogate established hepatitis C virus infection.
de Jong YP, Dorner M, Mommersteeg MC, Xiao JW, Balazs AB, Robbins JB, Winer BY, Gerges S, Vega K, Labitt RN, Donovan BM, Giang E, Krishnan A, Chiriboga L, Charlton MR, Burton DR, Baltimore D, Law M, Rice CM, Ploss A. de Jong YP, et al. Among authors: chiriboga l. Sci Transl Med. 2014 Sep 17;6(254):254ra129. doi: 10.1126/scitranslmed.3009512. Sci Transl Med. 2014. PMID: 25232181 Free PMC article.
Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice.
Scull MA, Shi C, de Jong YP, Gerold G, Ries M, von Schaewen M, Donovan BM, Labitt RN, Horwitz JA, Gaska JM, Hrebikova G, Xiao JW, Flatley B, Fung C, Chiriboga L, Walker CM, Evans DT, Rice CM, Ploss A. Scull MA, et al. Among authors: chiriboga l. Hepatology. 2015 Jul;62(1):57-67. doi: 10.1002/hep.27773. Epub 2015 Apr 15. Hepatology. 2015. PMID: 25820364 Free PMC article.
Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States.
Zou C, El Dika I, Vercauteren KOA, Capanu M, Chou J, Shia J, Pilet J, Quirk C, Lalazar G, Andrus L, Kabbani M, Yaqubie A, Khalil D, Mergoub T, Chiriboga L, Rice CM, Abou-Alfa GK, de Jong YP. Zou C, et al. Among authors: chiriboga l. Cancer Med. 2022 Feb;11(3):602-617. doi: 10.1002/cam4.4375. Epub 2021 Dec 24. Cancer Med. 2022. PMID: 34951132 Free PMC article.
Mouse models of acute and chronic hepacivirus infection.
Billerbeck E, Wolfisberg R, Fahnøe U, Xiao JW, Quirk C, Luna JM, Cullen JM, Hartlage AS, Chiriboga L, Ghoshal K, Lipkin WI, Bukh J, Scheel TKH, Kapoor A, Rice CM. Billerbeck E, et al. Among authors: chiriboga l. Science. 2017 Jul 14;357(6347):204-208. doi: 10.1126/science.aal1962. Science. 2017. PMID: 28706073 Free PMC article.
Keratin 19 and mesenchymal markers for evaluation of epithelial-mesenchymal transition and stem cell niche components in primary biliary cholangitis by sequential elution-stripping multiplex immunohistochemistry.
Paulsen JD, Zeck B, Sun K, Simoes C, Theise ND, Chiriboga L. Paulsen JD, et al. Among authors: chiriboga l. J Histotechnol. 2020 Dec;43(4):163-173. doi: 10.1080/01478885.2020.1807228. Epub 2020 Oct 1. J Histotechnol. 2020. PMID: 32998669 Free PMC article.
137 results