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Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
Huynh MV, Parsonage D, Forshaw TE, Chirasani VR, Hobbs GA, Wu H, Lee J, Furdui CM, Poole LB, Campbell SL. Huynh MV, et al. Among authors: chirasani vr. J Biol Chem. 2022 Aug;298(8):102186. doi: 10.1016/j.jbc.2022.102186. Epub 2022 Jun 24. J Biol Chem. 2022. PMID: 35753348 Free PMC article.
Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Murphy BM, Terrell EM, Chirasani VR, Weiss TJ, Lew RE, Holderbaum AM, Dhakal A, Posada V, Fort M, Bodnar MS, Carey LM, Chen M, Burd CJ, Coppola V, Morrison DK, Campbell SL, Burd CE. Murphy BM, et al. Among authors: chirasani vr. Nat Commun. 2022 Jun 7;13(1):3153. doi: 10.1038/s41467-022-30881-9. Nat Commun. 2022. PMID: 35672316 Free PMC article.
Two-input protein logic gate for computation in living cells.
Vishweshwaraiah YL, Chen J, Chirasani VR, Tabdanov ED, Dokholyan NV. Vishweshwaraiah YL, et al. Among authors: chirasani vr. Nat Commun. 2021 Nov 16;12(1):6615. doi: 10.1038/s41467-021-26937-x. Nat Commun. 2021. PMID: 34785644 Free PMC article.
Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation.
Allu PK, Chirasani VR, Ghosh D, Mani A, Bera AK, Maji SK, Senapati S, Mullasari AS, Mahapatra NR. Allu PK, et al. Among authors: chirasani vr. J Biol Chem. 2014 Feb 14;289(7):4455-69. doi: 10.1074/jbc.M113.520916. Epub 2013 Dec 12. J Biol Chem. 2014. PMID: 24338022 Free PMC article. Clinical Trial.
33 results