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Page 1
Organoid models of human and mouse ductal pancreatic cancer.
Boj SF, Hwang CI, Baker LA, Chio II, Engle DD, Corbo V, Jager M, Ponz-Sarvise M, Tiriac H, Spector MS, Gracanin A, Oni T, Yu KH, van Boxtel R, Huch M, Rivera KD, Wilson JP, Feigin ME, Öhlund D, Handly-Santana A, Ardito-Abraham CM, Ludwig M, Elyada E, Alagesan B, Biffi G, Yordanov GN, Delcuze B, Creighton B, Wright K, Park Y, Morsink FH, Molenaar IQ, Borel Rinkes IH, Cuppen E, Hao Y, Jin Y, Nijman IJ, Iacobuzio-Donahue C, Leach SD, Pappin DJ, Hammell M, Klimstra DS, Basturk O, Hruban RH, Offerhaus GJ, Vries RG, Clevers H, Tuveson DA. Boj SF, et al. Among authors: chio ii. Cell. 2015 Jan 15;160(1-2):324-38. doi: 10.1016/j.cell.2014.12.021. Epub 2014 Dec 31. Cell. 2015. PMID: 25557080 Free PMC article.
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC. Yun J, et al. Among authors: chio ii. Science. 2015 Dec 11;350(6266):1391-6. doi: 10.1126/science.aaa5004. Epub 2015 Nov 5. Science. 2015. PMID: 26541605 Free PMC article.
Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.
Dominguez-Brauer C, Hao Z, Elia AJ, Fortin JM, Nechanitzky R, Brauer PM, Sheng Y, Mana MD, Chio IIC, Haight J, Pollett A, Cairns R, Tworzyanski L, Inoue S, Reardon C, Marques A, Silvester J, Cox MA, Wakeham A, Yilmaz OH, Sabatini DM, van Es JH, Clevers H, Sato T, Mak TW. Dominguez-Brauer C, et al. Cell Stem Cell. 2016 Aug 4;19(2):205-216. doi: 10.1016/j.stem.2016.04.002. Epub 2016 May 12. Cell Stem Cell. 2016. PMID: 27184401 Free PMC article.
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.
Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, Wilkinson JE, Buscaglia JM, DeNicola GM, Tiriac H, Hammell M, Crawford HC, Schmidt EE, Thompson CB, Pappin DJ, Sonenberg N, Tuveson DA. Chio IIC, et al. Cell. 2016 Aug 11;166(4):963-976. doi: 10.1016/j.cell.2016.06.056. Epub 2016 Jul 28. Cell. 2016. PMID: 27477511 Free PMC article.
ROS in translation: Chink in the armor.
Chio II, Tuveson DA. Chio II, et al. Cell Cycle. 2017 Feb 16;16(4):297-298. doi: 10.1080/15384101.2016.1232087. Epub 2016 Sep 16. Cell Cycle. 2017. PMID: 27636545 Free PMC article. No abstract available.
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA. Öhlund D, et al. Among authors: chio ii. J Exp Med. 2017 Mar 6;214(3):579-596. doi: 10.1084/jem.20162024. Epub 2017 Feb 23. J Exp Med. 2017. PMID: 28232471 Free PMC article.
ROS in Cancer: The Burning Question.
Chio IIC, Tuveson DA. Chio IIC, et al. Trends Mol Med. 2017 May;23(5):411-429. doi: 10.1016/j.molmed.2017.03.004. Epub 2017 Apr 17. Trends Mol Med. 2017. PMID: 28427863 Free PMC article. Review.
Transcriptional Regulation by Nrf2.
Tonelli C, Chio IIC, Tuveson DA. Tonelli C, et al. Antioxid Redox Signal. 2018 Dec 10;29(17):1727-1745. doi: 10.1089/ars.2017.7342. Epub 2017 Oct 20. Antioxid Redox Signal. 2018. PMID: 28899199 Free PMC article. Review.
Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer.
Ponz-Sarvise M, Corbo V, Tiriac H, Engle DD, Frese KK, Oni TE, Hwang CI, Öhlund D, Chio IIC, Baker LA, Filippini D, Wright K, Bapiro TE, Huang P, Smith P, Yu KH, Jodrell DI, Park Y, Tuveson DA. Ponz-Sarvise M, et al. Clin Cancer Res. 2019 Nov 15;25(22):6742-6755. doi: 10.1158/1078-0432.CCR-19-1398. Epub 2019 Sep 6. Clin Cancer Res. 2019. PMID: 31492749 Free PMC article.
32 results