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Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Chee JM, Lanoue L, Clary D, Higgins K, Bower L, Flenniken A, Guo R, Adams DJ, Bosch F, Braun RE, Brown SDM, Chin HG, Dickinson ME, Hsu CW, Dobbie M, Gao X, Galande S, Grobler A, Heaney JD, Herault Y, de Angelis MH, Mammano F, Nutter LMJ, Parkinson H, Qin C, Shiroishi T, Sedlacek R, Seong JK, Xu Y; International Mouse Phenotyping Consortium; Brooks B, McKerlie C, Lloyd KCK, Westerberg H, Moshiri A. Chee JM, et al. Among authors: chin hg. BMC Biol. 2023 Feb 3;21(1):22. doi: 10.1186/s12915-022-01475-0. BMC Biol. 2023. PMID: 36737727 Free PMC article.
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes.
Higgins K, Moore BA, Berberovic Z, Adissu HA, Eskandarian M, Flenniken AM, Shao A, Imai DM, Clary D, Lanoue L, Newbigging S, Nutter LMJ, Adams DJ, Bosch F, Braun RE, Brown SDM, Dickinson ME, Dobbie M, Flicek P, Gao X, Galande S, Grobler A, Heaney JD, Herault Y, de Angelis MH, Chin HG, Mammano F, Qin C, Shiroishi T, Sedlacek R, Seong JK, Xu Y; IMPC Consortium; Lloyd KCK, McKerlie C, Moshiri A. Higgins K, et al. Among authors: chin hg. Sci Rep. 2022 Dec 1;12(1):20791. doi: 10.1038/s41598-022-19710-7. Sci Rep. 2022. PMID: 36456625 Free PMC article.
Factor quinolinone inhibitors disrupt spindles and multiple LSF (TFCP2)-protein interactions in mitosis, including with microtubule-associated proteins.
Yunes SA, Willoughby JLS, Kwan JH, Biagi JM, Pokharel N, Chin HG, York EA, Su KC, George K, Shah JV, Emili A, Schaus SE, Hansen U. Yunes SA, et al. Among authors: chin hg. PLoS One. 2022 Jun 15;17(6):e0268857. doi: 10.1371/journal.pone.0268857. eCollection 2022. PLoS One. 2022. PMID: 35704642 Free PMC article.
Polyglutamylation: biology and analysis.
Ruse CI, Chin HG, Pradhan S. Ruse CI, et al. Among authors: chin hg. Amino Acids. 2022 Apr;54(4):529-542. doi: 10.1007/s00726-022-03146-4. Epub 2022 Mar 31. Amino Acids. 2022. PMID: 35357568 Free PMC article. Review.
A resource of targeted mutant mouse lines for 5,061 genes.
Birling MC, Yoshiki A, Adams DJ, Ayabe S, Beaudet AL, Bottomley J, Bradley A, Brown SDM, Bürger A, Bushell W, Chiani F, Chin HG, Christou S, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Donahue LR, Fray MD, Gambadoro A, Gao X, Gertsenstein M, Gomez-Segura A, Goodwin LO, Heaney JD, Hérault Y, de Angelis MH, Jiang ST, Justice MJ, Kasparek P, King RE, Kühn R, Lee H, Lee YJ, Liu Z, Lloyd KCK, Lorenzo I, Mallon AM, McKerlie C, Meehan TF, Fuentes VM, Newman S, Nutter LMJ, Oh GT, Pavlovic G, Ramirez-Solis R, Rosen B, Ryder EJ, Santos LA, Schick J, Seavitt JR, Sedlacek R, Seisenberger C, Seong JK, Skarnes WC, Sorg T, Steel KP, Tamura M, Tocchini-Valentini GP, Wang CL, Wardle-Jones H, Wattenhofer-Donzé M, Wells S, Wiles MV, Willis BJ, Wood JA, Wurst W, Xu Y; International Mouse Phenotyping Consortium (IMPC); Teboul L, Murray SA. Birling MC, et al. Among authors: chin hg. Nat Genet. 2021 Apr;53(4):416-419. doi: 10.1038/s41588-021-00825-y. Nat Genet. 2021. PMID: 33833456 Free PMC article.
50 results