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Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Among authors: chin cv. Nature. 2023 Mar;615(7950):143-150. doi: 10.1038/s41586-023-05697-2. Epub 2023 Jan 11. Nature. 2023. PMID: 36630998
Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus.
Chen DY, Turcinovic J, Feng S, Kenney DJ, Chin CV, Choudhary MC, Conway HL, Semaan M, Close BJ, Tavares AH, Seitz S, Khan N, Kapell S, Crossland NA, Li JZ, Douam F, Baker SC, Connor JH, Saeed M. Chen DY, et al. Among authors: chin cv. iScience. 2023 May 19;26(5):106634. doi: 10.1016/j.isci.2023.106634. Epub 2023 Apr 10. iScience. 2023. PMID: 37095858 Free PMC article.
Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron.
Chen DY, Kenney D, Chin CV, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Among authors: chin cv. bioRxiv [Preprint]. 2023 Jan 10:2022.10.13.512134. doi: 10.1101/2022.10.13.512134. bioRxiv. 2023. PMID: 36263066 Free PMC article. Preprint.
Cohesin Mutations in Cancer: Emerging Therapeutic Targets.
Antony J, Chin CV, Horsfield JA. Antony J, et al. Among authors: chin cv. Int J Mol Sci. 2021 Jun 24;22(13):6788. doi: 10.3390/ijms22136788. Int J Mol Sci. 2021. PMID: 34202641 Free PMC article. Review.
Cohesin mutations are synthetic lethal with stimulation of WNT signaling.
Chin CV, Antony J, Ketharnathan S, Labudina A, Gimenez G, Parsons KM, He J, George AJ, Pallotta MM, Musio A, Braithwaite A, Guilford P, Hannan RD, Horsfield JA. Chin CV, et al. Elife. 2020 Dec 7;9:e61405. doi: 10.7554/eLife.61405. Elife. 2020. PMID: 33284104 Free PMC article.