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Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.
Fiorani P, Tesauro C, Mancini G, Chillemi G, D'Annessa I, Graziani G, Tentori L, Muzi A, Desideri A. Fiorani P, et al. Among authors: chillemi g. Nucleic Acids Res. 2009 Nov;37(20):6849-58. doi: 10.1093/nar/gkp669. Epub 2009 Sep 18. Nucleic Acids Res. 2009. PMID: 19767617 Free PMC article.
191 results