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Infant out-of-hospital cardiac arrest during nights and weekends.
Shekhar AC, Childers MK, Abbott EE, Kimbrell J, Coute RA, Mader TJ, Mann NC, Madhok M. Shekhar AC, et al. Among authors: childers mk. Am J Emerg Med. 2024 May 9;82:1-3. doi: 10.1016/j.ajem.2024.05.002. Online ahead of print. Am J Emerg Med. 2024. PMID: 38749370
Safety and efficacy of gene replacement therapy for X-linked myotubular myopathy (ASPIRO): a multinational, open-label, dose-escalation trial.
Shieh PB, Kuntz NL, Dowling JJ, Müller-Felber W, Bönnemann CG, Seferian AM, Servais L, Smith BK, Muntoni F, Blaschek A, Foley AR, Saade DN, Neuhaus S, Alfano LN, Beggs AH, Buj-Bello A, Childers MK, Duong T, Graham RJ, Jain M, Coats J, MacBean V, James ES, Lee J, Mavilio F, Miller W, Varfaj F, Murtagh M, Han C, Noursalehi M, Lawlor MW, Prasad S, Rico S. Shieh PB, et al. Among authors: childers mk. Lancet Neurol. 2023 Dec;22(12):1125-1139. doi: 10.1016/S1474-4422(23)00313-7. Lancet Neurol. 2023. PMID: 37977713 Free article. Clinical Trial.
Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes.
Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, Childers MK, Denning C, Day JW, Wu JC, Pruitt BL, Blau HM. Chang ACY, et al. Among authors: childers mk. Stem Cell Reports. 2021 Sep 14;16(9):2169-2181. doi: 10.1016/j.stemcr.2021.04.018. Epub 2021 May 20. Stem Cell Reports. 2021. PMID: 34019816 Free PMC article.
Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells.
Pioner JM, Guan X, Klaiman JM, Racca AW, Pabon L, Muskheli V, Macadangdang J, Ferrantini C, Hoopmann MR, Moritz RL, Kim DH, Tesi C, Poggesi C, Murry CE, Childers MK, Mack DL, Regnier M. Pioner JM, et al. Among authors: childers mk. Cardiovasc Res. 2020 Feb 1;116(2):368-382. doi: 10.1093/cvr/cvz109. Cardiovasc Res. 2020. PMID: 31049579 Free PMC article.
Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy.
Aminzadeh MA, Rogers RG, Fournier M, Tobin RE, Guan X, Childers MK, Andres AM, Taylor DJ, Ibrahim A, Ding X, Torrente A, Goldhaber JM, Lewis M, Gottlieb RA, Victor RA, Marbán E. Aminzadeh MA, et al. Among authors: childers mk. Stem Cell Reports. 2018 Mar 13;10(3):942-955. doi: 10.1016/j.stemcr.2018.01.023. Epub 2018 Mar 1. Stem Cell Reports. 2018. PMID: 29478899 Free PMC article.
Long-term effects of systemic gene therapy in a canine model of myotubular myopathy.
Elverman M, Goddard MA, Mack D, Snyder JM, Lawlor MW, Meng H, Beggs AH, Buj-Bello A, Poulard K, Marsh AP, Grange RW, Kelly VE, Childers MK. Elverman M, et al. Among authors: childers mk. Muscle Nerve. 2017 Nov;56(5):943-953. doi: 10.1002/mus.25658. Epub 2017 May 22. Muscle Nerve. 2017. PMID: 28370029 Free PMC article.
Systemic AAV8-Mediated Gene Therapy Drives Whole-Body Correction of Myotubular Myopathy in Dogs.
Mack DL, Poulard K, Goddard MA, Latournerie V, Snyder JM, Grange RW, Elverman MR, Denard J, Veron P, Buscara L, Le Bec C, Hogrel JY, Brezovec AG, Meng H, Yang L, Liu F, O'Callaghan M, Gopal N, Kelly VE, Smith BK, Strande JL, Mavilio F, Beggs AH, Mingozzi F, Lawlor MW, Buj-Bello A, Childers MK. Mack DL, et al. Among authors: childers mk. Mol Ther. 2017 Apr 5;25(4):839-854. doi: 10.1016/j.ymthe.2017.02.004. Epub 2017 Feb 22. Mol Ther. 2017. PMID: 28237839 Free PMC article.
86 results