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Epigenetic profiling with ultralow DNA amounts.
Lin FM, Chien S, Chen Z. Lin FM, et al. Among authors: chien s. Nat Biomed Eng. 2018 Mar;2(3):146-147. doi: 10.1038/s41551-018-0211-4. Nat Biomed Eng. 2018. PMID: 31015721 No abstract available.
Shear stress, SIRT1, and vascular homeostasis.
Chen Z, Peng IC, Cui X, Li YS, Chien S, Shyy JY. Chen Z, et al. Among authors: chien s. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10268-73. doi: 10.1073/pnas.1003833107. Epub 2010 May 17. Proc Natl Acad Sci U S A. 2010. PMID: 20479254 Free PMC article.
Shear stress activation of nuclear receptor PXR in endothelial detoxification.
Wang X, Fang X, Zhou J, Chen Z, Zhao B, Xiao L, Liu A, Li YS, Shyy JY, Guan Y, Chien S, Wang N. Wang X, et al. Among authors: chien s. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13174-9. doi: 10.1073/pnas.1312065110. Epub 2013 Jul 22. Proc Natl Acad Sci U S A. 2013. PMID: 23878263 Free PMC article.
Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a.
Chen Z, Wen L, Martin M, Hsu CY, Fang L, Lin FM, Lin TY, Geary MJ, Geary GG, Zhao Y, Johnson DA, Chen JW, Lin SJ, Chien S, Huang HD, Miller YI, Huang PH, Shyy JY. Chen Z, et al. Among authors: chien s. Circulation. 2015 Mar 3;131(9):805-14. doi: 10.1161/CIRCULATIONAHA.114.013675. Epub 2014 Dec 30. Circulation. 2015. PMID: 25550450 Free PMC article.
TIFA as a crucial mediator for NLRP3 inflammasome.
Lin TY, Wei TW, Li S, Wang SC, He M, Martin M, Zhang J, Shentu TP, Xiao H, Kang J, Wang KC, Chen Z, Chien S, Tsai MD, Shyy JY. Lin TY, et al. Among authors: chien s. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15078-15083. doi: 10.1073/pnas.1618773114. Epub 2016 Dec 13. Proc Natl Acad Sci U S A. 2016. PMID: 27965388 Free PMC article.
Epigenetic Regulation: A New Frontier for Biomedical Engineers.
Chen Z, Li S, Subramaniam S, Shyy JY, Chien S. Chen Z, et al. Among authors: chien s. Annu Rev Biomed Eng. 2017 Jun 21;19:195-219. doi: 10.1146/annurev-bioeng-071516-044720. Epub 2017 Mar 6. Annu Rev Biomed Eng. 2017. PMID: 28301736 Review.
1,595 results