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Efficacy and safety exposure-response relationships of apalutamide in patients with metastatic castration-sensitive prostate cancer: results from the phase 3 TITAN study.
T'jollyn H, Ackaert O, Chien C, Lopez-Gitlitz A, McCarthy S, Ruixo CP, Karsh L, Chi K, Chowdhury S, Ruixo JP, Agarwal N. T'jollyn H, et al. Among authors: chien c. Cancer Chemother Pharmacol. 2022 May;89(5):629-641. doi: 10.1007/s00280-022-04427-1. Epub 2022 Apr 2. Cancer Chemother Pharmacol. 2022. PMID: 35366072 Clinical Trial.
Pharmacokinetics, Safety, and Antitumor Effect of Apalutamide with Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer: Phase Ib Study.
Posadas EM, Chi KN, de Wit R, de Jonge MJA, Attard G, Friedlander TW, Yu MK, Hellemans P, Chien C, Abrams C, Jiao JJ, Saad F. Posadas EM, et al. Among authors: chien c. Clin Cancer Res. 2020 Jul 15;26(14):3517-3524. doi: 10.1158/1078-0432.CCR-19-3402. Epub 2020 May 4. Clin Cancer Res. 2020. PMID: 32366670 Clinical Trial.
Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy.
Genovese MC, Hsia E, Belkowski SM, Chien C, Masterson T, Thurmond RL, Manthey CL, Yan XD, Ge T, Franks C, Greenspan A. Genovese MC, et al. Among authors: chien c. J Rheumatol. 2015 Oct;42(10):1752-60. doi: 10.3899/jrheum.141580. Epub 2015 Aug 1. J Rheumatol. 2015. PMID: 26233509 Free article. Clinical Trial.
An open-label, multicenter, phase Ib study investigating the effect of apalutamide on ventricular repolarization in men with castration-resistant prostate cancer.
Belderbos BPSI, de Wit R, Chien C, Mitselos A, Hellemans P, Jiao J, Yu MK, Attard G, Bulat I, Edenfield WJ, Saad F. Belderbos BPSI, et al. Among authors: chien c. Cancer Chemother Pharmacol. 2018 Sep;82(3):457-468. doi: 10.1007/s00280-018-3632-6. Epub 2018 Jul 5. Cancer Chemother Pharmacol. 2018. PMID: 29974203 Free PMC article. Clinical Trial.
Food effects on abiraterone pharmacokinetics in healthy subjects and patients with metastatic castration-resistant prostate cancer.
Chi KN, Spratlin J, Kollmannsberger C, North S, Pankras C, Gonzalez M, Bernard A, Stieltjes H, Peng L, Jiao J, Acharya M, Kheoh T, Griffin TW, Yu MK, Chien C, Tran NP. Chi KN, et al. Among authors: chien c. J Clin Pharmacol. 2015 Dec;55(12):1406-14. doi: 10.1002/jcph.564. Epub 2015 Jul 23. J Clin Pharmacol. 2015. PMID: 26096139 Clinical Trial.
Efficacy and Safety Exposure-Response Relationships of Apalutamide in Patients with Nonmetastatic Castration-Resistant Prostate Cancer.
Perez-Ruixo C, Ackaert O, Ouellet D, Chien C, Uemura H, Olmos D, Mainwaring P, Lee JY, Yu MK, Perez-Ruixo JJ, Smith MR, Small EJ. Perez-Ruixo C, et al. Among authors: chien c. Clin Cancer Res. 2020 Sep 1;26(17):4460-4467. doi: 10.1158/1078-0432.CCR-20-1041. Epub 2020 Jun 19. Clin Cancer Res. 2020. PMID: 32561663 Free article. Clinical Trial.
2,842 results