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Investigative safety science as a competitive advantage for Pharma.
Moggs J, Moulin P, Pognan F, Brees D, Leonard M, Busch S, Cordier A, Heard DJ, Kammüller M, Merz M, Bouchard P, Chibout SD. Moggs J, et al. Among authors: chibout sd. Expert Opin Drug Metab Toxicol. 2012 Sep;8(9):1071-82. doi: 10.1517/17425255.2012.693914. Epub 2012 Jul 7. Expert Opin Drug Metab Toxicol. 2012. PMID: 22769724 Review.
Safety differentiation: emerging competitive edge in drug development.
Uteng M, Urban L, Brees D, Muller PY, Kullak-Ublick GA, Bouchard P, Tougas G, Chibout SD. Uteng M, et al. Among authors: chibout sd. Drug Discov Today. 2019 Jan;24(1):285-292. doi: 10.1016/j.drudis.2018.09.009. Epub 2018 Sep 19. Drug Discov Today. 2019. PMID: 30244081 Free article. Review.
Mapping the epigenome--impact for toxicology.
Marlowe J, Teo SS, Chibout SD, Pognan F, Moggs J. Marlowe J, et al. Among authors: chibout sd. EXS. 2009;99:259-88. doi: 10.1007/978-3-7643-8336-7_10. EXS. 2009. PMID: 19157065 Review.
Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human.
Pognan F, Mahl JA, Papoutsi M, Ledieu D, Raccuglia M, Theil D, Voytek SB, Devine PJ, Kubek-Luck K, Claudio N, Cordier A, Heier A, Kolly C, Hartmann A, Chibout SD, Bouchard P, Trendelenburg C. Pognan F, et al. Among authors: chibout sd. Arch Toxicol. 2018 May;92(5):1877-1891. doi: 10.1007/s00204-018-2189-9. Epub 2018 Mar 19. Arch Toxicol. 2018. PMID: 29556671 Free PMC article.
Bile acids in drug induced liver injury: Key players and surrogate markers.
Schadt HS, Wolf A, Pognan F, Chibout SD, Merz M, Kullak-Ublick GA. Schadt HS, et al. Among authors: chibout sd. Clin Res Hepatol Gastroenterol. 2016 Jun;40(3):257-266. doi: 10.1016/j.clinre.2015.12.017. Epub 2016 Feb 10. Clin Res Hepatol Gastroenterol. 2016. PMID: 26874804 Free article. Review.
47 results