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A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis.
Pradella D, Deflorian G, Pezzotta A, Di Matteo A, Belloni E, Campolungo D, Paradisi A, Bugatti M, Vermi W, Campioni M, Chiapparino A, Scietti L, Forneris F, Giampietro C, Volf N, Rehman M, Zacchigna S, Paronetto MP, Pistocchi A, Eichmann A, Mehlen P, Ghigna C. Pradella D, et al. Among authors: chiapparino a. Nat Commun. 2021 Aug 11;12(1):4872. doi: 10.1038/s41467-021-24998-6. Nat Commun. 2021. PMID: 34381052 Free PMC article.
A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing.
Angiolini F, Belloni E, Giordano M, Campioni M, Forneris F, Paronetto MP, Lupia M, Brandas C, Pradella D, Di Matteo A, Giampietro C, Jodice G, Luise C, Bertalot G, Freddi S, Malinverno M, Irimia M, Moulton JD, Summerton J, Chiapparino A, Ghilardi C, Giavazzi R, Nyqvist D, Gabellini D, Dejana E, Cavallaro U, Ghigna C. Angiolini F, et al. Among authors: chiapparino a. Elife. 2019 Mar 4;8:e44305. doi: 10.7554/eLife.44305. Elife. 2019. PMID: 30829570 Free PMC article.
A Fe2+-dependent self-inhibited state influences the druggability of human collagen lysyl hydroxylase (LH/PLOD) enzymes.
Scietti L, Moroni E, Mattoteia D, Fumagalli M, De Marco M, Negro L, Chiapparino A, Serapian SA, De Giorgi F, Faravelli S, Colombo G, Forneris F. Scietti L, et al. Among authors: chiapparino a. Front Mol Biosci. 2022 Aug 25;9:876352. doi: 10.3389/fmolb.2022.876352. eCollection 2022. Front Mol Biosci. 2022. PMID: 36090047 Free PMC article.
23 results