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Safety and efficacy of sargramostim (GM-CSF) in the treatment of Alzheimer's disease.
Potter H, Woodcock JH, Boyd TD, Coughlan CM, O'Shaughnessy JR, Borges MT, Thaker AA, Raj BA, Adamszuk K, Scott D, Adame V, Anton P, Chial HJ, Gray H, Daniels J, Stocker ME, Sillau SH. Potter H, et al. Among authors: chial hj. Alzheimers Dement (N Y). 2021 Mar 24;7(1):e12158. doi: 10.1002/trc2.12158. eCollection 2021. Alzheimers Dement (N Y). 2021. PMID: 33778150 Free PMC article.
Exosomal biomarkers in Down syndrome and Alzheimer's disease.
Hamlett ED, Ledreux A, Potter H, Chial HJ, Patterson D, Espinosa JM, Bettcher BM, Granholm AC. Hamlett ED, et al. Among authors: chial hj. Free Radic Biol Med. 2018 Jan;114:110-121. doi: 10.1016/j.freeradbiomed.2017.08.028. Epub 2017 Sep 5. Free Radic Biol Med. 2018. PMID: 28882786 Free PMC article. Review.
Proteasome activity modulates amyloid toxicity.
Galvin J, Curran E, Arteaga F, Goossens A, Aubuchon-Endsley N, McMurray MA, Moore J, Hansen KC, Chial HJ, Potter H, Brodsky JL, Coughlan CM. Galvin J, et al. Among authors: chial hj. FEMS Yeast Res. 2022 Mar 9;22(1):foac004. doi: 10.1093/femsyr/foac004. FEMS Yeast Res. 2022. PMID: 35150241 Free PMC article.
The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice.
Ahmed MM, Wang AC, Elos M, Chial HJ, Sillau S, Solano DA, Coughlan C, Aghili L, Anton P, Markham N, Adame V, Gardiner KJ, Boyd TD, Potter H. Ahmed MM, et al. Among authors: chial hj. Neurobiol Dis. 2022 Jun 15;168:105694. doi: 10.1016/j.nbd.2022.105694. Epub 2022 Mar 18. Neurobiol Dis. 2022. PMID: 35307513 Free PMC article.
38 results