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The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation.
Fiorito V, Allocco AL, Petrillo S, Gazzano E, Torretta S, Marchi S, Destefanis F, Pacelli C, Audrito V, Provero P, Medico E, Chiabrando D, Porporato PE, Cancelliere C, Bardelli A, Trusolino L, Capitanio N, Deaglio S, Altruda F, Pinton P, Cardaci S, Riganti C, Tolosano E. Fiorito V, et al. Among authors: chiabrando d. Cell Rep. 2021 Jun 15;35(11):109252. doi: 10.1016/j.celrep.2021.109252. Cell Rep. 2021. PMID: 34133926 Free article.
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation.
Chiabrando D, Marro S, Mercurio S, Giorgi C, Petrillo S, Vinchi F, Fiorito V, Fagoonee S, Camporeale A, Turco E, Merlo GR, Silengo L, Altruda F, Pinton P, Tolosano E. Chiabrando D, et al. J Clin Invest. 2012 Dec;122(12):4569-79. doi: 10.1172/JCI62422. Epub 2012 Nov 26. J Clin Invest. 2012. PMID: 23187127 Free PMC article.
Heme and erythropoieis: more than a structural role.
Chiabrando D, Mercurio S, Tolosano E. Chiabrando D, et al. Haematologica. 2014 Jun;99(6):973-83. doi: 10.3324/haematol.2013.091991. Haematologica. 2014. PMID: 24881043 Free PMC article. Review.
The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation.
Mercurio S, Petrillo S, Chiabrando D, Bassi ZI, Gays D, Camporeale A, Vacaru A, Miniscalco B, Valperga G, Silengo L, Altruda F, Baron MH, Santoro MM, Tolosano E. Mercurio S, et al. Among authors: chiabrando d. Haematologica. 2015 Jun;100(6):720-9. doi: 10.3324/haematol.2014.114488. Epub 2015 Mar 20. Haematologica. 2015. PMID: 25795718 Free PMC article.
28 results