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High-throughput protein purification and quality assessment for crystallization.
Kim Y, Babnigg G, Jedrzejczak R, Eschenfeldt WH, Li H, Maltseva N, Hatzos-Skintges C, Gu M, Makowska-Grzyska M, Wu R, An H, Chhor G, Joachimiak A. Kim Y, et al. Among authors: chhor g. Methods. 2011 Sep;55(1):12-28. doi: 10.1016/j.ymeth.2011.07.010. Epub 2011 Aug 31. Methods. 2011. PMID: 21907284 Free PMC article. Review.
Salvage of failed protein targets by reductive alkylation.
Tan K, Kim Y, Hatzos-Skintges C, Chang C, Cuff M, Chhor G, Osipiuk J, Michalska K, Nocek B, An H, Babnigg G, Bigelow L, Joachimiak G, Li H, Mack J, Makowska-Grzyska M, Maltseva N, Mulligan R, Tesar C, Zhou M, Joachimiak A. Tan K, et al. Among authors: chhor g. Methods Mol Biol. 2014;1140:189-200. doi: 10.1007/978-1-4939-0354-2_15. Methods Mol Biol. 2014. PMID: 24590719 Free PMC article.
RsaM: a transcriptional regulator of Burkholderia spp. with novel fold.
Michalska K, Chhor G, Clancy S, Jedrzejczak R, Babnigg G, Winans SC, Joachimiak A. Michalska K, et al. Among authors: chhor g. FEBS J. 2014 Sep;281(18):4293-306. doi: 10.1111/febs.12868. Epub 2014 Jul 4. FEBS J. 2014. PMID: 24916958 Free PMC article.
New aminopeptidase from "microbial dark matter" archaeon.
Michalska K, Steen AD, Chhor G, Endres M, Webber AT, Bird J, Lloyd KG, Joachimiak A. Michalska K, et al. Among authors: chhor g. FASEB J. 2015 Sep;29(9):4071-9. doi: 10.1096/fj.15-272906. Epub 2015 Jun 10. FASEB J. 2015. PMID: 26062601 Free PMC article.
Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712.
Breinlinger E, Van Epps S, Friedman M, Argiriadi M, Chien E, Chhor G, Cowart M, Dunstan T, Graff C, Hardee D, Herold JM, Little A, McCarthy R, Parmentier J, Perham M, Qiu W, Schrimpf M, Vargo T, Webster MP, Wu F, Bennett D, Edmunds J. Breinlinger E, et al. Among authors: chhor g. J Med Chem. 2023 Oct 26;66(20):14335-14356. doi: 10.1021/acs.jmedchem.3c01373. Epub 2023 Oct 12. J Med Chem. 2023. PMID: 37823891
11 results