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The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial.
Clin Cancer Res. 2021 Dec 1;27(23):6500-6513. doi: 10.1158/1078-0432.CCR-21-1652. Epub 2021 Sep 8.
Clin Cancer Res. 2021.
PMID: 34497073
Free PMC article.
Ancient and modern: hints of a core post-transcriptional network driving chemotherapy resistance in ovarian cancer.
Blagden S, Abdel Mouti M, Chettle J.
Blagden S, et al. Among authors: chettle j.
Wiley Interdiscip Rev RNA. 2018 Jan;9(1):e1432. doi: 10.1002/wrna.1432. Epub 2017 Aug 1.
Wiley Interdiscip Rev RNA. 2018.
PMID: 28762650
Free PMC article.
Review.
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LARP1 isoform expression in human cancer cell lines.
Schwenzer H, Abdel Mouti M, Neubert P, Morris J, Stockton J, Bonham S, Fellermeyer M, Chettle J, Fischer R, Beggs AD, Blagden SP.
Schwenzer H, et al. Among authors: chettle j.
RNA Biol. 2021 Feb;18(2):237-247. doi: 10.1080/15476286.2020.1744320. Epub 2020 Apr 14.
RNA Biol. 2021.
PMID: 32286153
Free PMC article.
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Controversies around the function of LARP1.
Berman AJ, Thoreen CC, Dedeic Z, Chettle J, Roux PP, Blagden SP.
Berman AJ, et al. Among authors: chettle j.
RNA Biol. 2021 Feb;18(2):207-217. doi: 10.1080/15476286.2020.1733787. Epub 2020 Apr 1.
RNA Biol. 2021.
PMID: 32233986
Free PMC article.
Review.
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Pathology caused by persistent murine norovirus infection.
Shortland A, Chettle J, Archer J, Wood K, Bailey D, Goodfellow I, Blacklaws BA, Heeney JL.
Shortland A, et al. Among authors: chettle j.
J Gen Virol. 2014 Feb;95(Pt 2):413-422. doi: 10.1099/vir.0.059188-0. Epub 2013 Nov 13.
J Gen Virol. 2014.
PMID: 24225497
Free PMC article.
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Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance.
Swamy M, Abeler-Dörner L, Chettle J, Mahlakõiv T, Goubau D, Chakravarty P, Ramsay G, Reis e Sousa C, Staeheli P, Blacklaws BA, Heeney JL, Hayday AC.
Swamy M, et al. Among authors: chettle j.
Nat Commun. 2015 May 19;6:7090. doi: 10.1038/ncomms8090.
Nat Commun. 2015.
PMID: 25987506
Free PMC article.
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In vitro reconstruction of tetronate RK-682 biosynthesis.
Sun Y, Hahn F, Demydchuk Y, Chettle J, Tosin M, Osada H, Leadlay PF.
Sun Y, et al. Among authors: chettle j.
Nat Chem Biol. 2010 Feb;6(2):99-101. doi: 10.1038/nchembio.285. Epub 2009 Dec 20.
Nat Chem Biol. 2010.
PMID: 20081823
Free PMC article.
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