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Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice.
Jarvis R, Josephine Ng SF, Nathanson AJ, Cardarelli RA, Abiraman K, Wade F, Evans-Strong A, Fernandez-Campa MP, Deeb TZ, Smalley JL, Jamier T, Gurrell IK, McWilliams L, Kawatkar A, Conway LC, Wang Q, Burli RW, Brandon NJ, Chessell IP, Goldman AJ, Maguire JL, Moss SJ. Jarvis R, et al. Among authors: chessell ip. Cell Rep Med. 2023 Mar 21;4(3):100957. doi: 10.1016/j.xcrm.2023.100957. Epub 2023 Mar 7. Cell Rep Med. 2023. PMID: 36889319 Free PMC article.
Sensitization of colonic nociceptors by IL-13 is dependent on JAK and p38 MAPK activity.
Barker KH, Higham JP, Pattison LA, Chessell IP, Welsh F, Smith ESJ, Bulmer DC. Barker KH, et al. Among authors: chessell ip. Am J Physiol Gastrointest Liver Physiol. 2023 Apr 1;324(4):G250-G261. doi: 10.1152/ajpgi.00280.2022. Epub 2023 Feb 7. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36749569 Free PMC article.
Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine.
Kopruszinski CM, Thornton P, Arnold J, Newton P, Lowne D, Navratilova E, Swiokla J, Dodick DW, Dobson C, Gurrell I, Chessell IP, Porreca F. Kopruszinski CM, et al. Among authors: chessell ip. Cephalalgia. 2020 Dec;40(14):1535-1550. doi: 10.1177/0333102420966581. Epub 2020 Nov 1. Cephalalgia. 2020. PMID: 33131305
The Dementias Platform UK (DPUK) Data Portal.
Bauermeister S, Orton C, Thompson S, Barker RA, Bauermeister JR, Ben-Shlomo Y, Brayne C, Burn D, Campbell A, Calvin C, Chandran S, Chaturvedi N, Chêne G, Chessell IP, Corbett A, Davis DHJ, Denis M, Dufouil C, Elliott P, Fox N, Hill D, Hofer SM, Hu MT, Jindra C, Kee F, Kim CH, Kim C, Kivimaki M, Koychev I, Lawson RA, Linden GJ, Lyons RA, Mackay C, Matthews PM, McGuiness B, Middleton L, Moody C, Moore K, Na DL, O'Brien JT, Ourselin S, Paranjothy S, Park KS, Porteous DJ, Richards M, Ritchie CW, Rohrer JD, Rossor MN, Rowe JB, Scahill R, Schnier C, Schott JM, Seo SW, South M, Steptoe M, Tabrizi SJ, Tales A, Tillin T, Timpson NJ, Toga AW, Visser PJ, Wade-Martins R, Wilkinson T, Williams J, Wong A, Gallacher JEJ. Bauermeister S, et al. Among authors: chessell ip. Eur J Epidemiol. 2020 Jun;35(6):601-611. doi: 10.1007/s10654-020-00633-4. Epub 2020 Apr 23. Eur J Epidemiol. 2020. PMID: 32328990 Free PMC article.
Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP4 receptor partial agonist for the treatment of pain.
Healy MP, Allan AC, Bailey K, Billinton A, Chessell IP, Clayton NM, Giblin GMP, Kay MA, Khaznadar T, Michel AD, Naylor A, Price H, Spalding DJ, Stevens DA, Swarbrick ME, Wilson AW. Healy MP, et al. Among authors: chessell ip. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1892-1896. doi: 10.1016/j.bmcl.2018.03.091. Epub 2018 Mar 31. Bioorg Med Chem Lett. 2018. PMID: 29636218
Comparison between semiquantitative and quantitative methods for the assessment of knee synovitis in osteoarthritis using non-enhanced and gadolinium-enhanced MRI.
Crema MD, Roemer FW, Li L, Alexander RC, Chessell IP, Dudley AD, Karlsten R, Rosen LB, Guermazi A. Crema MD, et al. Among authors: chessell ip. Osteoarthritis Cartilage. 2017 Feb;25(2):267-271. doi: 10.1016/j.joca.2016.09.016. Epub 2016 Sep 30. Osteoarthritis Cartilage. 2017. PMID: 27697506 Free article.
The Expression of Inflammatory Mediators in Bladder Pain Syndrome.
Offiah I, Didangelos A, Dawes J, Cartwright R, Khullar V, Bradbury EJ, O'Sullivan S, Williams D, Chessell IP, Pallas K, Graham G, O'Reilly BA, McMahon SB. Offiah I, et al. Among authors: chessell ip. Eur Urol. 2016 Aug;70(2):283-90. doi: 10.1016/j.eururo.2016.02.058. Epub 2016 Mar 7. Eur Urol. 2016. PMID: 26965559 Free PMC article.
99 results