Cheong J - Search Results

1

Novel antibody-antibiotic conjugate eliminates intracellular S. aureus.

Lehar SM, Pillow T, Xu M, Staben L, Kajihara KK, Vandlen R, DePalatis L, Raab H, Hazenbos WL, Morisaki JH, Kim J, Park S, Darwish M, Lee BC, Hernandez H, Loyet KM, Lupardus P, Fong R, Yan D, Chalouni C, Luis E, Khalfin Y, Plise E, Cheong J, Lyssikatos JP, Strandh M, Koefoed K, Andersen PS, Flygare JA, Wah Tan M, Brown EJ, Mariathasan S. Lehar SM, et al. Among authors: cheong j. Nature. 2015 Nov 19;527(7578):323-8. doi: 10.1038/nature16057. Epub 2015 Nov 4. Nature. 2015. PMID: 26536114

2

Evaluating the in vitro inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in predicting drug-induced hyperbilirubinemia.

Chang JH, Plise E, Cheong J, Ho Q, Lin M. Chang JH, et al. Among authors: cheong j. Mol Pharm. 2013 Aug 5;10(8):3067-75. doi: 10.1021/mp4001348. Epub 2013 Jun 21. Mol Pharm. 2013. PMID: 23750830

3

Differential effects of Rifampin and Ketoconazole on the blood and liver concentration of atorvastatin in wild-type and Cyp3a and Oatp1a/b knockout mice.

Chang JH, Ly J, Plise E, Zhang X, Messick K, Wright M, Cheong J. Chang JH, et al. Among authors: cheong j. Drug Metab Dispos. 2014 Jun;42(6):1067-73. doi: 10.1124/dmd.114.057968. Epub 2014 Mar 26. Drug Metab Dispos. 2014. PMID: 24671957

4

Practical permeability-based hepatic clearance classification system (HepCCS) in drug discovery.

Fan PW, Song Y, Berezhkovskiy LM, Cheong J, Plise EG, Khojasteh SC. Fan PW, et al. Among authors: cheong j. Future Med Chem. 2014;6(18):1995-2012. doi: 10.4155/fmc.14.141. Future Med Chem. 2014. PMID: 25531965

5

Predicting Passive Permeability of Drug-like Molecules from Chemical Structure: Where Are We?

Broccatelli F, Salphati L, Plise E, Cheong J, Gobbi A, Lee ML, Aliagas I. Broccatelli F, et al. Among authors: cheong j. Mol Pharm. 2016 Dec 5;13(12):4199-4208. doi: 10.1021/acs.molpharmaceut.6b00836. Epub 2016 Nov 11. Mol Pharm. 2016. PMID: 27806577

6

The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters.

Cheong J, Halladay JS, Plise E, Sodhi JK, Salphati L. Cheong J, et al. Drug Metab Lett. 2017;11(2):111-118. doi: 10.2174/1872312811666171010101248. Drug Metab Lett. 2017. PMID: 29032766

7

Evaluating the Utility of Canine Mdr1 Knockout Madin-Darby Canine Kidney I Cells in Permeability Screening and Efflux Substrate Determination.

Chen EC, Broccatelli F, Plise E, Chen B, Liu L, Cheong J, Zhang S, Jorski J, Gaffney K, Umemoto KK, Salphati L. Chen EC, et al. Among authors: cheong j. Mol Pharm. 2018 Nov 5;15(11):5103-5113. doi: 10.1021/acs.molpharmaceut.8b00688. Epub 2018 Oct 10. Mol Pharm. 2018. PMID: 30222362

8

Preclinical characterization of the absorption and disposition of the brain penetrant PI3K/mTOR inhibitor paxalisib and prediction of its pharmacokinetics and efficacy in human.

Salphati L, Pang J, Alicke B, Plise EG, Cheong J, Jaochico A, Olivero AG, Sampath D, Wong S, Zhang X. Salphati L, et al. Among authors: cheong j. Xenobiotica. 2024 Feb;54(2):64-74. doi: 10.1080/00498254.2024.2303586. Epub 2024 Jan 15. Xenobiotica. 2024. PMID: 38197324

9

The design and identification of brain penetrant inhibitors of phosphoinositide 3-kinase α.

Heffron TP, Salphati L, Alicke B, Cheong J, Dotson J, Edgar K, Goldsmith R, Gould SE, Lee LB, Lesnick JD, Lewis C, Ndubaku C, Nonomiya J, Olivero AG, Pang J, Plise EG, Sideris S, Trapp S, Wallin J, Wang L, Zhang X. Heffron TP, et al. Among authors: cheong j. J Med Chem. 2012 Sep 27;55(18):8007-20. doi: 10.1021/jm300867c. Epub 2012 Sep 11. J Med Chem. 2012. PMID: 22946614

10

Targeting the PI3K pathway in the brain--efficacy of a PI3K inhibitor optimized to cross the blood-brain barrier.

Salphati L, Heffron TP, Alicke B, Nishimura M, Barck K, Carano RA, Cheong J, Edgar KA, Greve J, Kharbanda S, Koeppen H, Lau S, Lee LB, Pang J, Plise EG, Pokorny JL, Reslan HB, Sarkaria JN, Wallin JJ, Zhang X, Gould SE, Olivero AG, Phillips HS. Salphati L, et al. Among authors: cheong j. Clin Cancer Res. 2012 Nov 15;18(22):6239-48. doi: 10.1158/1078-0432.CCR-12-0720. Epub 2012 Sep 19. Clin Cancer Res. 2012. PMID: 22992516

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