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p53-based cancer therapy.
Lane DP, Cheok CF, Lain S. Lane DP, et al. Among authors: cheok cf. Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a001222. doi: 10.1101/cshperspect.a001222. Epub 2010 May 12. Cold Spring Harb Perspect Biol. 2010. PMID: 20463003 Free PMC article. Review.
Reactivation of p53: from peptides to small molecules.
Brown CJ, Cheok CF, Verma CS, Lane DP. Brown CJ, et al. Among authors: cheok cf. Trends Pharmacol Sci. 2011 Jan;32(1):53-62. doi: 10.1016/j.tips.2010.11.004. Epub 2010 Dec 8. Trends Pharmacol Sci. 2011. PMID: 21145600 Review.
Mdm2 and p53 are highly conserved from placozoans to man.
Lane DP, Cheok CF, Brown C, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Among authors: cheok cf. Cell Cycle. 2010 Feb 1;9(3):540-7. doi: 10.4161/cc.9.3.10516. Cell Cycle. 2010. PMID: 20081368
The Mdm2 and p53 genes are conserved in the Arachnids.
Lane DP, Cheok CF, Brown CJ, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Among authors: cheok cf. Cell Cycle. 2010 Feb 15;9(4):748-54. doi: 10.4161/cc.9.4.10616. Epub 2010 Feb 12. Cell Cycle. 2010. PMID: 20160485
Translating p53 into the clinic.
Cheok CF, Verma CS, Baselga J, Lane DP. Cheok CF, et al. Nat Rev Clin Oncol. 2011 Jan;8(1):25-37. doi: 10.1038/nrclinonc.2010.174. Epub 2010 Oct 26. Nat Rev Clin Oncol. 2011. PMID: 20975744 Review.
New insights into p53 based therapy.
Lane DP, Brown CJ, Verma C, Cheok CF. Lane DP, et al. Among authors: cheok cf. Discov Med. 2011 Aug;12(63):107-17. Discov Med. 2011. PMID: 21878188 Free article. Review.
Exploiting the p53 Pathway for Therapy.
Cheok CF, Lane DP. Cheok CF, et al. Cold Spring Harb Perspect Med. 2017 Mar 1;7(3):a026310. doi: 10.1101/cshperspect.a026310. Cold Spring Harb Perspect Med. 2017. PMID: 28193768 Free PMC article. Review.
25 results