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Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum.
Kümpornsin K, Kochakarn T, Yeo T, Okombo J, Luth MR, Hoshizaki J, Rawat M, Pearson RD, Schindler KA, Mok S, Park H, Uhlemann AC, Jana GP, Maity BC, Laleu B, Chenu E, Duffy J, Moliner Cubel S, Franco V, Gomez-Lorenzo MG, Gamo FJ, Winzeler EA, Fidock DA, Chookajorn T, Lee MCS. Kümpornsin K, et al. Among authors: chenu e. Nat Commun. 2023 May 27;14(1):3059. doi: 10.1038/s41467-023-38774-1. Nat Commun. 2023. PMID: 37244916 Free PMC article.
Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2.
Laleu B, Rubiano K, Yeo T, Hallyburton I, Anderson M, Crespo-Fernandez B, Gamo FJ, Antonova-Koch Y, Orjuela-Sanchez P, Wittlin S, Jana GP, Maity BC, Chenu E, Duffy J, Sjö P, Waterson D, Winzeler E, Guantai E, Fidock DA, Hansson TG. Laleu B, et al. Among authors: chenu e. ChemMedChem. 2022 Nov 18;17(22):e202200393. doi: 10.1002/cmdc.202200393. Epub 2022 Oct 13. ChemMedChem. 2022. PMID: 36129427 Free PMC article.
Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out.
Dechering KJ, Timmerman M, Rensen K, Koolen KMJ, Honarnejad S, Vos MW, Huijs T, Henderson RWM, Chenu E, Laleu B, Montefiore BC, Segall MD, Mills JEJ, Guantai EM, Duffy J, Duffey M. Dechering KJ, et al. Among authors: chenu e. SLAS Discov. 2022 Sep;27(6):337-348. doi: 10.1016/j.slasd.2022.07.002. Epub 2022 Jul 21. SLAS Discov. 2022. PMID: 35872229 Free article.
MAIP: An Open-Source Tool to Enrich High-Throughput Screening Output and Identify Novel, Druglike Molecules with Antimalarial Activity.
Bosc N, Felix E, Gardner JMF, Mills J, Timmerman M, Asveld D, Rensen K, Mukherjee P, Das R, Chenu E, Besson D, Burrows JN, Duffy J, Laleu B, Guantai EM, Leach AR. Bosc N, et al. Among authors: chenu e. ACS Med Chem Lett. 2023 Nov 20;14(12):1733-1741. doi: 10.1021/acsmedchemlett.3c00369. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116432 Free PMC article.
Age-associated cerebral atrophy in mouse lemur primates.
Kraska A, Dorieux O, Picq JL, Petit F, Bourrin E, Chenu E, Volk A, Perret M, Hantraye P, Mestre-Frances N, Aujard F, Dhenain M. Kraska A, et al. Among authors: chenu e. Neurobiol Aging. 2011 May;32(5):894-906. doi: 10.1016/j.neurobiolaging.2009.05.018. Epub 2009 Jun 28. Neurobiol Aging. 2011. PMID: 19564059 Free PMC article.
The Rieske/cytochrome b complex of Heliobacteria.
Ducluzeau AL, Chenu E, Capowiez L, Baymann F. Ducluzeau AL, et al. Among authors: chenu e. Biochim Biophys Acta. 2008 Sep;1777(9):1140-6. doi: 10.1016/j.bbabio.2008.04.026. Epub 2008 Apr 23. Biochim Biophys Acta. 2008. PMID: 18474216 Free article.
46 results