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Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4.
Chauhan J, Grandits M, Palhares LCGF, Mele S, Nakamura M, López-Abente J, Crescioli S, Laddach R, Romero-Clavijo P, Cheung A, Stavraka C, Chenoweth AM, Sow HS, Chiaruttini G, Gilbert AE, Dodev T, Koers A, Pellizzari G, Ilieva KM, Man F, Ali N, Hobbs C, Lombardi S, Lionarons DA, Gould HJ, Beavil AJ, Geh JLC, MacKenzie Ross AD, Healy C, Calonje E, Downward J, Nestle FO, Tsoka S, Josephs DH, Blower PJ, Karagiannis P, Lacy KE, Spicer J, Karagiannis SN, Bax HJ. Chauhan J, et al. Among authors: chenoweth am. Nat Commun. 2023 Apr 25;14(1):2192. doi: 10.1038/s41467-023-37811-3. Nat Commun. 2023. PMID: 37185332 Free PMC article.
Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action.
Willsmore ZN, Coumbe BGT, Crescioli S, Reci S, Gupta A, Harris RJ, Chenoweth A, Chauhan J, Bax HJ, McCraw A, Cheung A, Osborn G, Hoffmann RM, Nakamura M, Laddach R, Geh JLC, MacKenzie-Ross A, Healy C, Tsoka S, Spicer JF, Josephs DH, Papa S, Lacy KE, Karagiannis SN. Willsmore ZN, et al. Eur J Immunol. 2021 Mar;51(3):544-556. doi: 10.1002/eji.202048747. Epub 2021 Feb 23. Eur J Immunol. 2021. PMID: 33450785 Free article. Review.
B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies.
Willsmore ZN, Harris RJ, Crescioli S, Hussein K, Kakkassery H, Thapa D, Cheung A, Chauhan J, Bax HJ, Chenoweth A, Laddach R, Osborn G, McCraw A, Hoffmann RM, Nakamura M, Geh JL, MacKenzie-Ross A, Healy C, Tsoka S, Spicer JF, Papa S, Barber L, Lacy KE, Karagiannis SN. Willsmore ZN, et al. Front Immunol. 2021 Jan 25;11:622442. doi: 10.3389/fimmu.2020.622442. eCollection 2020. Front Immunol. 2021. PMID: 33569063 Free PMC article. Review.
Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer.
Harris RJ, Cheung A, Ng JCF, Laddach R, Chenoweth AM, Crescioli S, Fittall M, Dominguez-Rodriguez D, Roberts J, Levi D, Liu F, Alberts E, Quist J, Santaolalla A, Pinder SE, Gillett C, Hammar N, Irshad S, Van Hemelrijck M, Dunn-Walters DK, Fraternali F, Spicer JF, Lacy KE, Tsoka S, Grigoriadis A, Tutt ANJ, Karagiannis SN. Harris RJ, et al. Among authors: chenoweth am. Cancer Res. 2021 Aug 15;81(16):4290-4304. doi: 10.1158/0008-5472.CAN-20-3773. Epub 2021 Jun 15. Cancer Res. 2021. PMID: 34224371 Free PMC article.
Antibodies to watch in 2022.
Kaplon H, Chenoweth A, Crescioli S, Reichert JM. Kaplon H, et al. MAbs. 2022 Jan-Dec;14(1):2014296. doi: 10.1080/19420862.2021.2014296. MAbs. 2022. PMID: 35030985 Free PMC article. Review.
CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models.
Cheung A, Chenoweth AM, Quist J, Sow HS, Malaktou C, Ferro R, Hoffmann RM, Osborn G, Sachouli E, French E, Marlow R, Lacy KE, Papa S, Grigoriadis A, Karagiannis SN. Cheung A, et al. Among authors: chenoweth am. Cancers (Basel). 2022 Jul 11;14(14):3361. doi: 10.3390/cancers14143361. Cancers (Basel). 2022. PMID: 35884422 Free PMC article.
Influencing tumor-associated macrophages in malignant melanoma with monoclonal antibodies.
Adams R, Osborn G, Mukhia B, Laddach R, Willsmore Z, Chenoweth A, Geh JLC, MacKenzie Ross AD, Healy C, Barber L, Tsoka S, Sanz-Moreno V, Lacy KE, Karagiannis SN. Adams R, et al. Oncoimmunology. 2022 Oct 3;11(1):2127284. doi: 10.1080/2162402X.2022.2127284. eCollection 2022. Oncoimmunology. 2022. PMID: 36211808 Free PMC article. Review.
23 results