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Molecular mechanisms of coronary artery disease risk at the PDGFD locus.
Kim HJ, Cheng P, Travisano S, Weldy C, Monteiro JP, Kundu R, Nguyen T, Sharma D, Shi H, Lin Y, Liu B, Haldar S, Jackson S, Quertermous T. Kim HJ, et al. Among authors: cheng p. Nat Commun. 2023 Feb 15;14(1):847. doi: 10.1038/s41467-023-36518-9. Nat Commun. 2023. PMID: 36792607 Free PMC article.
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.
Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T. Iyer D, et al. Among authors: cheng p. PLoS Genet. 2018 Oct 11;14(10):e1007681. doi: 10.1371/journal.pgen.1007681. eCollection 2018 Oct. PLoS Genet. 2018. PMID: 30307970 Free PMC article.
Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm.
Pedroza AJ, Tashima Y, Shad R, Cheng P, Wirka R, Churovich S, Nakamura K, Yokoyama N, Cui JZ, Iosef C, Hiesinger W, Quertermous T, Fischbein MP. Pedroza AJ, et al. Among authors: cheng p. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):2195-2211. doi: 10.1161/ATVBAHA.120.314670. Epub 2020 Jul 23. Arterioscler Thromb Vasc Biol. 2020. PMID: 32698686 Free PMC article.
ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis.
Cheng P, Wirka RC, Shoa Clarke L, Zhao Q, Kundu R, Nguyen T, Nair S, Sharma D, Kim HJ, Shi H, Assimes T, Brian Kim J, Kundaje A, Quertermous T. Cheng P, et al. Circulation. 2022 Feb 8;145(6):469-485. doi: 10.1161/CIRCULATIONAHA.121.057789. Epub 2022 Jan 6. Circulation. 2022. PMID: 34990206 Free PMC article.
Embryologic Origin Influences Smooth Muscle Cell Phenotypic Modulation Signatures in Murine Marfan Syndrome Aortic Aneurysm.
Pedroza AJ, Dalal AR, Shad R, Yokoyama N, Nakamura K, Cheng P, Wirka RC, Mitchel O, Baiocchi M, Hiesinger W, Quertermous T, Fischbein MP. Pedroza AJ, et al. Among authors: cheng p. Arterioscler Thromb Vasc Biol. 2022 Sep;42(9):1154-1168. doi: 10.1161/ATVBAHA.122.317381. Epub 2022 Jul 7. Arterioscler Thromb Vasc Biol. 2022. PMID: 35861960 Free PMC article.
4,611 results