Cheng F - Search Results

1

Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease.

Fang J, Zhang P, Zhou Y, Chiang CW, Tan J, Hou Y, Stauffer S, Li L, Pieper AA, Cummings J, Cheng F. Fang J, et al. Among authors: cheng f. Nat Aging. 2021 Dec;1(12):1175-1188. doi: 10.1038/s43587-021-00138-z. Epub 2021 Dec 6. Nat Aging. 2021. PMID: 35572351 Free PMC article. Clinical Trial.

2

In silico polypharmacology of natural products.

Fang J, Liu C, Wang Q, Lin P, Cheng F. Fang J, et al. Among authors: cheng f. Brief Bioinform. 2018 Nov 27;19(6):1153-1171. doi: 10.1093/bib/bbx045. Brief Bioinform. 2018. PMID: 28460068 Review.

3

In Silico Pharmacoepidemiologic Evaluation of Drug-Induced Cardiovascular Complications Using Combined Classifiers.

Cai C, Fang J, Guo P, Wang Q, Hong H, Moslehi J, Cheng F. Cai C, et al. Among authors: cheng f. J Chem Inf Model. 2018 May 29;58(5):943-956. doi: 10.1021/acs.jcim.7b00641. Epub 2018 May 10. J Chem Inf Model. 2018. PMID: 29712429 Free PMC article.

4

Quantitative and systems pharmacology 4. Network-based analysis of drug pleiotropy on coronary artery disease.

Fang J, Cai C, Chai Y, Zhou J, Huang Y, Gao L, Wang Q, Cheng F. Fang J, et al. Among authors: cheng f. Eur J Med Chem. 2019 Jan 1;161:192-204. doi: 10.1016/j.ejmech.2018.10.020. Epub 2018 Oct 15. Eur J Med Chem. 2019. PMID: 30359818 Free PMC article.

5

Deep Learning-Based Prediction of Drug-Induced Cardiotoxicity.

Cai C, Guo P, Zhou Y, Zhou J, Wang Q, Zhang F, Fang J, Cheng F. Cai C, et al. Among authors: cheng f. J Chem Inf Model. 2019 Mar 25;59(3):1073-1084. doi: 10.1021/acs.jcim.8b00769. Epub 2019 Feb 15. J Chem Inf Model. 2019. PMID: 30715873 Free PMC article.

6

A component overlapping attribute clustering (COAC) algorithm for single-cell RNA sequencing data analysis and potential pathobiological implications.

Peng H, Zeng X, Zhou Y, Zhang D, Nussinov R, Cheng F. Peng H, et al. Among authors: cheng f. PLoS Comput Biol. 2019 Feb 19;15(2):e1006772. doi: 10.1371/journal.pcbi.1006772. eCollection 2019 Feb. PLoS Comput Biol. 2019. PMID: 30779739 Free PMC article.

7

deepDR: a network-based deep learning approach to in silico drug repositioning.

Zeng X, Zhu S, Liu X, Zhou Y, Nussinov R, Cheng F. Zeng X, et al. Among authors: cheng f. Bioinformatics. 2019 Dec 15;35(24):5191-5198. doi: 10.1093/bioinformatics/btz418. Bioinformatics. 2019. PMID: 31116390 Free PMC article.

8

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.

Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. Huang Y, et al. Among authors: cheng f. Cell Chem Biol. 2019 Aug 15;26(8):1143-1158.e6. doi: 10.1016/j.chembiol.2019.05.004. Epub 2019 Jun 6. Cell Chem Biol. 2019. PMID: 31178408 Free PMC article.

9

A genome-wide positioning systems network algorithm for in silico drug repurposing.

Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy DE, Wang R, Zhao Y, Yang Y, Huang J, Hill DE, Vidal M, Eng C, Loscalzo J. Cheng F, et al. Nat Commun. 2019 Aug 2;10(1):3476. doi: 10.1038/s41467-019-10744-6. Nat Commun. 2019. PMID: 31375661 Free PMC article.

10

A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications.

Jin S, Zeng X, Fang J, Lin J, Chan SY, Erzurum SC, Cheng F. Jin S, et al. Among authors: cheng f. NPJ Syst Biol Appl. 2019 Nov 13;5:41. doi: 10.1038/s41540-019-0115-2. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 31754458 Free PMC article.

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