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Fortuitous somatic mutations during antibody evolution endow broad neutralization against SARS-CoV-2 Omicron variants.
Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L, Sun L, Wang Q. Wu J, et al. Among authors: chen z. Cell Rep. 2023 May 30;42(5):112503. doi: 10.1016/j.celrep.2023.112503. Epub 2023 May 3. Cell Rep. 2023. PMID: 37178120 Free PMC article.
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Liu Z, Xu W, Chen Z, Fu W, Zhan W, Gao Y, Zhou J, Zhou Y, Wu J, Wang Q, Zhang X, Hao A, Wu W, Zhang Q, Li Y, Fan K, Chen R, Jiang Q, Mayer CT, Schoofs T, Xie Y, Jiang S, Wen Y, Yuan Z, Wang K, Lu L, Sun L, Wang Q. Liu Z, et al. Among authors: chen z, chen r. Protein Cell. 2022 Sep;13(9):655-675. doi: 10.1007/s13238-021-00871-6. Epub 2021 Sep 23. Protein Cell. 2022. PMID: 34554412 Free PMC article.
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Li C, Zhan W, Yang Z, Tu C, Hu G, Zhang X, Song W, Du S, Zhu Y, Huang K, Kong Y, Zhang M, Mao Q, Gu X, Zhang Y, Xie Y, Deng Q, Song Y, Chen Z, Lu L, Jiang S, Wu Y, Sun L, Ying T. Li C, et al. Among authors: chen z. Cell. 2022 Apr 14;185(8):1389-1401.e18. doi: 10.1016/j.cell.2022.03.009. Epub 2022 Mar 10. Cell. 2022. PMID: 35344711 Free PMC article.
Fortuitous Somatic Mutations during Antibody Evolution Endow Broad Neutralization against SARS-CoV-2 Omicron Variants.
Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L, Sun L, Wang Q. Wu J, et al. Among authors: chen z. bioRxiv [Preprint]. 2022 Dec 13:2022.12.12.520172. doi: 10.1101/2022.12.12.520172. bioRxiv. 2022. PMID: 36561175 Free PMC article. Updated. Preprint.
Characterization of cross-reactive monoclonal antibodies against SARS-CoV-1 and SARS-CoV-2: Implication for rational design and development of pan-sarbecovirus vaccines and neutralizing antibodies.
Li S, Wu J, Jiang W, He H, Zhou Y, Wu W, Gao Y, Xie M, Xia A, He J, Zhang Q, Han Y, Wang N, Zhu G, Wang Q, Zhang Z, Mayer CT, Wang K, Wang X, Wang J, Chen Z, Jiang S, Sun L, Xia R, Wang Q. Li S, et al. Among authors: chen z. J Med Virol. 2023 Feb;95(2):e28440. doi: 10.1002/jmv.28440. J Med Virol. 2023. PMID: 36573441 Free PMC article.
Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Liu Q, Zhang X, Huang H, Chen Y, Wang F, Hao A, Zhan W, Mao Q, Hu Y, Han L, Sun Y, Zhang M, Liu Z, Li GL, Zhang W, Shu Y, Sun L, Chen Z. Liu Q, et al. Among authors: chen z, chen y. Nat Commun. 2023 May 25;14(1):3012. doi: 10.1038/s41467-023-38303-0. Nat Commun. 2023. PMID: 37230976 Free PMC article.
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