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Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis.
Feng X, Szulzewsky F, Yerevanian A, Chen Z, Heinzmann D, Rasmussen RD, Alvarez-Garcia V, Kim Y, Wang B, Tamagno I, Zhou H, Li X, Kettenmann H, Ransohoff RM, Hambardzumyan D. Feng X, et al. Among authors: chen z. Oncotarget. 2015 Jun 20;6(17):15077-94. doi: 10.18632/oncotarget.3730. Oncotarget. 2015. PMID: 25987130 Free PMC article.
Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma.
Sadahiro H, Kang KD, Gibson JT, Minata M, Yu H, Shi J, Chhipa R, Chen Z, Lu S, Simoni Y, Furuta T, Sabit H, Zhang S, Bastola S, Yamaguchi S, Alsheikh H, Komarova S, Wang J, Kim SH, Hambardzumyan D, Lu X, Newell EW, DasGupta B, Nakada M, Lee LJ, Nabors B, Norian LA, Nakano I. Sadahiro H, et al. Among authors: chen z. Cancer Res. 2018 Jun 1;78(11):3002-3013. doi: 10.1158/0008-5472.CAN-17-2433. Epub 2018 Mar 12. Cancer Res. 2018. PMID: 29531161 Free PMC article.
Immune Microenvironment in Glioblastoma Subtypes.
Chen Z, Hambardzumyan D. Chen Z, et al. Front Immunol. 2018 May 8;9:1004. doi: 10.3389/fimmu.2018.01004. eCollection 2018. Front Immunol. 2018. PMID: 29867979 Free PMC article. Review.
Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage V, Semtner M, Vidal RO, Hernandez DP, Pong WW, Chen Z, Hambardzumyan D, Magrini V, Ly A, Walker J, Mardis E, Mertins P, Sauer S, Kettenmann H, Gutmann DH. Haage V, et al. Among authors: chen z. Acta Neuropathol Commun. 2019 Feb 14;7(1):20. doi: 10.1186/s40478-019-0665-y. Acta Neuropathol Commun. 2019. PMID: 30764877 Free PMC article.
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes I, Szulzewsky F, Chen Z, Herting CJ, Gabanic B, Velázquez Vega JE, Shelton J, Switchenko JM, Ross JL, McSwain LF, Huse JT, Westermark B, Nelander S, Forsberg-Nilsson K, Uhrbom L, Maturi NP, Cimino PJ, Holland EC, Kettenmann H, Brennan CW, Brat DJ, Hambardzumyan D. Kaffes I, et al. Among authors: chen z. Oncoimmunology. 2019 Aug 22;8(11):e1655360. doi: 10.1080/2162402X.2019.1655360. eCollection 2019. Oncoimmunology. 2019. PMID: 31646100 Free PMC article.
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