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Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.
Riedmaier AE, DeMent K, Huckle J, Bransford P, Stillhart C, Lloyd R, Alluri R, Basu S, Chen Y, Dhamankar V, Dodd S, Kulkarni P, Olivares-Morales A, Peng CC, Pepin X, Ren X, Tran T, Tistaert C, Heimbach T, Kesisoglou F, Wagner C, Parrott N. Riedmaier AE, et al. Among authors: chen y. AAPS J. 2020 Sep 27;22(6):123. doi: 10.1208/s12248-020-00508-2. AAPS J. 2020. PMID: 32981010 Free PMC article.
Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry Perspective.
Bohnert T, Patel A, Templeton I, Chen Y, Lu C, Lai G, Leung L, Tse S, Einolf HJ, Wang YH, Sinz M, Stearns R, Walsky R, Geng W, Sudsakorn S, Moore D, He L, Wahlstrom J, Keirns J, Narayanan R, Lang D, Yang X; International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Victim Drug-Drug Interactions Working Group. Bohnert T, et al. Among authors: chen y. Drug Metab Dispos. 2016 Aug;44(8):1399-423. doi: 10.1124/dmd.115.069096. Epub 2016 Apr 6. Drug Metab Dispos. 2016. PMID: 27052879 Review.
Quantitative Prediction of Drug-Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?
Templeton IE, Chen Y, Mao J, Lin J, Yu H, Peters S, Shebley M, Varma MV. Templeton IE, et al. Among authors: chen y. CPT Pharmacometrics Syst Pharmacol. 2016 Oct;5(10):505-515. doi: 10.1002/psp4.12110. Epub 2016 Sep 19. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27642087 Free PMC article.
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