Chen XH - Search Results

1

Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors.

Guo AD, Yan KN, Hu H, Zhai L, Hu TF, Su H, Chi Y, Zha J, Xu Y, Zhao D, Lu X, Xu YJ, Zhang J, Tan M, Chen XH. Guo AD, et al. Among authors: chen xh. Nat Chem. 2023 Jun;15(6):803-814. doi: 10.1038/s41557-023-01196-z. Epub 2023 Apr 27. Nat Chem. 2023. PMID: 37106095

2

The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L.

Hao BB, Li XJ, Jia XL, Wang YX, Zhai LH, Li DZ, Liu J, Zhang D, Chen YL, Xu YH, Lee SK, Xu GF, Chen XH, Dang YJ, Liu B, Tan MJ. Hao BB, et al. Among authors: chen xh, chen yl. Acta Pharmacol Sin. 2020 Sep;41(9):1246-1254. doi: 10.1038/s41401-020-0367-9. Epub 2020 Mar 24. Acta Pharmacol Sin. 2020. PMID: 32210356 Free PMC article.

3

Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation.

Guo AD, Wei D, Nie HJ, Hu H, Peng C, Li ST, Yan KN, Zhou BS, Feng L, Fang C, Tan M, Huang R, Chen XH. Guo AD, et al. Among authors: chen xh. Nat Commun. 2020 Oct 29;11(1):5472. doi: 10.1038/s41467-020-19274-y. Nat Commun. 2020. PMID: 33122644 Free PMC article.

4

Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer.

Wei D, Wang H, Zeng Q, Wang W, Hao B, Feng X, Wang P, Song N, Kan W, Huang G, Zhou X, Tan M, Zhou Y, Huang R, Li J, Chen XH. Wei D, et al. Among authors: chen xh. J Med Chem. 2021 Oct 14;64(19):14822-14847. doi: 10.1021/acs.jmedchem.1c01350. Epub 2021 Sep 20. J Med Chem. 2021. PMID: 34538051

5

Genetically Encoded Benzoyllysines Serve as Versatile Probes for Interrogating Histone Benzoylation and Interactions in Living Cells.

Tian H, Yang J, Guo AD, Ran Y, Yang YZ, Yang B, Huang R, Liu H, Chen XH. Tian H, et al. Among authors: chen xh. ACS Chem Biol. 2021 Nov 19;16(11):2560-2569. doi: 10.1021/acschembio.1c00614. Epub 2021 Oct 7. ACS Chem Biol. 2021. PMID: 34618427

6

Light-induced efficient and residue-selective bioconjugation of native proteins via indazolone formation.

Guo AD, Wu KH, Chen XH. Guo AD, et al. Among authors: chen xh. RSC Adv. 2021 Jan 11;11(4):2235-2241. doi: 10.1039/d0ra10154k. eCollection 2021 Jan 6. RSC Adv. 2021. PMID: 35424183 Free PMC article.

7

Rapid and halide compatible synthesis of 2-N-substituted indazolone derivatives via photochemical cyclization in aqueous media.

Nie HJ, Guo AD, Lin HX, Chen XH. Nie HJ, et al. Among authors: chen xh. RSC Adv. 2019 Apr 30;9(23):13249-13253. doi: 10.1039/c9ra02466b. eCollection 2019 Apr 25. RSC Adv. 2019. PMID: 35520758 Free PMC article.

8

Macrocyclizing DNA-Linked Peptides via Three-Component Cyclization and Photoinduced Chemistry.

Bao Y, Xing M, Matthew N, Chen X, Wang X, Lu X. Bao Y, et al. Org Lett. 2024 Apr 12;26(14):2763-2767. doi: 10.1021/acs.orglett.3c01817. Epub 2023 Jun 29. Org Lett. 2024. PMID: 37382883

9

Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells.

Hu H, Hu W, Guo AD, Zhai L, Ma S, Nie HJ, Zhou BS, Liu T, Jia X, Liu X, Yao X, Tan M, Chen XH. Hu H, et al. Among authors: chen xh. Nat Commun. 2024 Feb 17;15(1):1465. doi: 10.1038/s41467-024-45765-3. Nat Commun. 2024. PMID: 38368419 Free PMC article.

10

Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry.

Yan KN, Nie YQ, Wang JY, Yin GL, Liu Q, Hu H, Sun X, Chen XH. Yan KN, et al. Among authors: chen xh. Adv Sci (Weinh). 2024 Apr 30:e2400594. doi: 10.1002/advs.202400594. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38689503

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